Author: healthadmin

An ancient Chinese exercise routine that combines slow movement, controlled breathing, and meditation may lower blood pressure as effectively as a brisk walk, according to a large randomized clinical trial published in . jackthe flagship journal of the American College of Cardiology. Participants saw improvements within three months, and the benefits lasted for one year. High blood pressure remains one of the biggest preventable causes of heart disease. Doctors often recommend regular physical activity to manage symptoms, but many people have a hard time maintaining long-term exercise habits, especially when training requires a gym membership, special equipment, dedicated space, or…

After years of back and forth on how to use funds to address PFAS contamination, the state recently disbursed $133 million to help Wisconsin communities address widespread contamination from these “forever chemicals.” The money will support PFAS testing and remediation efforts across the state, including funding for new wells and provisions to protect “innocent landowners” who have contamination on their property through no fault of their own. Maine has followed this path. In 2021, state lawmakers passed a series of bills aimed at solving the state’s own PFAS crisis, which was caused in part by sewage sludge spreading on farms,…

CSL lowered its revenue forecast for the fiscal year to $15.2 billion from $15.8 billion, another sign of the company’s financial woes since its ill-fated $11.7 billion acquisition of Swiss iron deficiency and kidney disease specialist Before Pharma in 2022. In addition to revising its earnings forecast for CSL’s fiscal year (ending June 30), the company announced it will take a $5 billion asset impairment charge. This update is a review of the company’s financial position following the sudden departure in February of Dr. Paul McKenzie, who served as CEO for three years. CSL’s stock price fell about 16% on…

Targeted protein degradation is changing the way drug discovery teams think about disease biology. For many years, small molecule programs have been built around inhibition. The compound was expected to bind to disease-associated proteins and block their activity. This logic still works for many targets. However, this is not sufficient for proteins that lack distinct binding pockets, function primarily as scaffolds, or cause disease through non-enzymatic functions. Here, the degradation of the target protein becomes important. That asks a different question. Is it possible to not only block a protein, but also tell cells to remove it?Why target protein degradation…

With the program’s seventh approval, FDA is demonstrating how quickly it can review drugs that qualify for national priority testing in the United States. On Friday, two days after handing Partner Therapeutics the Secretary’s National Preference Voucher (CNPV), the FDA fully cleared the company’s bispecific antibody Bizengri as a second-line treatment for adults with advanced unresectable or metastatic cholangiocarcinoma harboring the NRG1 gene fusion. The green light in rare bile duct cancer marks Bizengri’s third indication, with first-in-class accelerated approvals in NRG1+ pancreatic adenocarcinoma and non-small cell lung cancer in late 2024. Partner Therapeutics worked closely with Bizengri’s initial approval…

Addressing long-term mental health recovery remains a major challenge as lives are increasingly disrupted by disasters, including displacement, conflict and climate-related emergencies. A communication from Juntendo University argues that while assessment of acute symptoms remains important, disaster psychiatry could benefit from a community-led approach to care. The authors discuss the importance of: ibasho (community spaces with a sense of belonging and social purpose) and suggest that rebuilding daily life, roles and neighborhood connections may support long-term recovery and resilience. Natural disasters have a major impact on human lives, destroying homes, separating families, disrupting daily life, and affecting stability. While emergency…

A growing body of research points out that fructose is more than just a source of additional calories. New report published natural metabolism It highlights the unique role of sugar in metabolic diseases and suggests that its effects on the body may be more harmful than previously understood. Researchers reviewed the evidence on commonly used sweeteners, such as sugar (sucrose) and high fructose corn syrup. Although both contain glucose and fructose, fructose behaves differently in the body and may play a more direct role in obesity and related health problems, scientists say. “Fructose is more than just a calorie,” says…

Daiichi Sankyo aims to transform its antibody-drug conjugate (ADC) leadership into a leading position in global oncology. In a new five-year business plan released on Monday, the Japanese drugmaker outlined a roadmap to become one of the world’s top five oncology companies by 2035 and a massive 200 billion yen ($1.3 billion) cost optimization plan. First, it expects its revenue to reach more than 3 trillion yen ($19.1 billion) by 2030 (PDF), 2.3 trillion yen of which will come from its oncology portfolio, which it hopes to expand with more than 20 new indications across five medicines. In fiscal 2025,…

Surgery is a complex task. Even if the surgery is successful, complications can occur, and even the best surgeons can fail. Surgeons must rely on visual cues and their own experience to avoid nerve or blood vessel damage. Mistakes can turn a simple surgery into a more difficult one. Unfortunately, many of these potential dangers lurk below the tissue surface and remain hidden from surgeons until modern imaging technology reveals them. Kai Zhang, associate professor at Worcester Polytechnic Institute, will present his research integrating photoacoustic (PA) imaging into robot-assisted surgery on Monday, May 11 at 8:40 a.m. ET as part…

New research published in Psychedelic Research Journal found that people who had meaningful psychedelic experiences reported a significantly reduced fear of death, as well as an increased sense of connection to themselves, others, and the world around them. Furthermore, the degree of connectedness closely tracks the degree of freedom from fear related to death. Researchers have long argued that death anxiety is at the root of an astonishing range of psychological struggles, from depression to broader existential distress. Studies have observed that psychedelic experiences (first noted in terminally ill patients in the mid-20th century and later confirmed in modern controlled…