Author: healthadmin

Sapio Sciences, an AI lab informatics company, today announced that Claude Cowork, Anthropic’s agent AI assistant, has been integrated into the Sapio platform through AI co-scientist Sapio Elain. This integration provides a single conversational interface for scientists and project leaders to search, retrieve, and analyze data held across their R&D organization and take actions directly within Sapio ELN and LIMS. Working autonomously on your behalf, Claude Cowork searches across data sources, collates results, and returns verified, structured output, reports, and dashboards. Connected to the Sapio platform, Claude Cowork can also perform actions on your behalf to manipulate ELN experiments and…

DeNovix Inc. has introduced a new product to its innovative collection of life science devices, the Squid™ full-range pipette. Image credit: DeNovix Inc. With an unprecedented 1-1000 µL volume range, Squid Pipette simplifies your laboratory by performing the tasks of traditional 3-5 pipettes in one device. Squid replaces switching pipettes during experiments and facilitates an efficient, distraction-free workflow. Squid’s unique performance is achieved through Dynamic Volume Control™, which combines a patented chip selector mechanism with DeNovix’s expertise in microvolume motor control. Two built-in tip modes, large (100 – 1000 μL) and small (1 – 200 μL), allow Squid to use…

A review of the extensive clinical trial landscape shows how CAR T therapies are moving beyond single-target designs to multifunctional “living drugs” designed to improve safety, overcome tumor escape, and tackle difficult-to-treat cancers. Review: Mapping the clinical landscape of multifunctional CAR T cells: targets, trends, and synergies In a comprehensive review recently published in the magazine molecular therapyGerman researchers analyzed 1,801 registered clinical trials to map the evolution of “next generation” chimeric antigen receptor (CAR) T cell products. The review found that multifunctional CAR T-cell therapies accounted for 533 of 1,801 CAR T trials, representing 33% of new CAR T…

Patient groups’ perceptions of drug companies with large U.S. footprints have changed over the past year as companies battle political pressure, PatientView said. The findings come from PatientView’s annual survey of more than 2,000 patient groups worldwide. The research firm found that patient groups “significantly changed their perceptions of the corporate reputations of many individual drug companies.” PatientView said such large year-over-year changes are rare and feedback suggests that “rapid changes in market conditions are the primary cause of the divergence.” The reputation rankings of pharmaceutical companies fluctuate, centering on companies with large bases in the United States. The change…

By mapping CAR-T cells one by one, researchers are uncovering cell characteristics that may differentiate between a sustained cancer response and recurrence. Review: Clinical CAR-T cell mapping: insights from scRNA-seq. Image credit: Nemes Laszlo / Shutterstock In a recent review published in a magazine Trends in molecular medicineUS researchers synthesized results from single-cell RNA sequencing (scRNA-seq; n = 44 studies) to identify transcriptional patterns associated with how well patients respond to CAR-T cell therapy. Single cell analysis of CAR-T responses Chimeric antigen receptor T cell (CAR-T) therapy is considered one of the breakthroughs of modern medicine. This treatment involves harvesting…

For the first time, scientists have clearly seen a subduction zone in the process of breaking up. These zones form where one plate sinks beneath another and are responsible for some of the most powerful geological phenomena on Earth. The new discovery is scientific progressprovides an unusual perspective on how these large-scale systems evolve and raises new questions about seismic risk in the Pacific Northwest. Subduction zones dramatically shape the Earth. They shift continents, cause massive earthquakes and volcanic eruptions, and pull old crust deep into the Earth’s mantle. But despite their great power, they don’t last forever. Why do…

By reengineering how engineered immune cells use glucose, fats and amino acids, researchers hope to help CAR-T therapies survive the hostile metabolism of solid tumors. Research: Metabolic reprogramming of CAR-T cells: a multipronged strategy to overcome the immunosuppressive tumor microenvironment. Image credit: Corona Borealis Studio / Shutterstock In a recent review published in a magazine Cell communication and signalingChinese researchers evaluated how metabolic reprogramming increases the efficacy of chimeric antigen receptor T cells (CAR-T cells) in harsh tumor environments. CAR-T metabolism in the solid tumor setting Why are some of the most advanced cancer treatments ineffective against solid tumors?Despite remarkable…

Critics warn that the federal bill, which preempts food safety laws in hundreds of states, would weaken consumer protections from toxic chemicals, but supporters say it would lower food costs and ease supply chain strain. At an April 29 press conference hosted by the Environmental Task Force, California Assemblyman Jesse Gabriel said the FDA’s Food Safety, Health, and Health (FRESH) and Affordable Review and Evaluation Act is a “Trojan horse for the food industry” and a “direct attack on the health and safety of children” that would repeal dozens of food safety laws passed in both red and blue states…

Responses to a national survey released today reveal tunnel construction workers across Australia say they face significant exposure to silica dust, a harmful dust that can cause incurable diseases such as silicosis and lung cancer. Research led by the University of Sydney Australian and New Zealand Journal of Public Health, The study is based on a survey of 290 tunneling industry workers and industry professionals from September 2024 to June 2025. This study highlights a potentially significant gap between awareness of silica risks and effective implementation of safety management. “Workers understand the risks, but our findings show that the systems…

The World Health Organization (WHO) has confirmed that Australia has eliminated trachoma as a public health problem, marking an important milestone in the global effort to improve the health of indigenous peoples and combat neglected tropical diseases (NTDs). Trachoma, the world’s leading infectious cause of blindness, is no longer a public health problem in this country. Australia joins a growing number of countries that have successfully eliminated trachoma and is contributing to global progress towards the targets set in the WHO NTDs Roadmap 2021-2030. trachoma is caused by bacteria chlamydia trachomatis It is spread by close contact with infected people,…