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Author: healthadmin
Novartis sticks to $5 billion Pluvicto target despite European regulatory setbacks and bispecific competition
Novartis CEO Basu Narasimhan is doubling down on Pluvicto’s $5 billion peak sales forecast, even though the company has given up on expanding the label in Europe. Novartis has withdrawn its application to the European Medicines Agency for Purvict as a pre-chemotherapy treatment for PSMA-positive metastatic castration-resistant prostate cancer (mCRPC), the companies announced on Friday. Narasimhan told reporters on a conference call Tuesday that the withdrawal “reflects a different perspective on what is an appropriate comparison in a pre-taxane situation.” Although the PSMAfore trial tested Pluvicto against a modified androgen receptor pathway inhibitor, some doctors argue that chemotherapy should be…
Frequent church attendance strongly predicts whether a woman will marry before having children
Analysis of National Youth Longitudinal Survey data examined the types of family formation transitions people experience. They found that women who frequently attend religious services or belong to conservative denominations were most likely to marry before cohabiting with a partner or having children. The paper was published in. Religious Science Research Journal. Family-forming events are life events in which people create, expand, or redefine family units. Usually includes marriage, cohabitation, and childbirth. Decades ago, most women in the United States married without cohabiting. These days, however, approximately 75% of young women live with a partner at some point in their…
Can compounds found in everyday soy-based foods help alleviate COPD symptoms? A new study reveals how diet, particularly isoflavones, plays a role in shaping respiratory health and disease burden in ex-smokers. Research: Isoflavone intake is associated with reduced incidence of chronic obstructive pulmonary disease. Image credit: Makistock/Shutterstock.com In recent research, Chronic obstructive pulmonary disease We evaluated whether increased dietary isoflavone intake was associated with improvement in respiratory disease in ex-smokers with chronic obstructive pulmonary disease (COPD). Dietary patterns and their impact on COPD risk and progression COPD is a progressive lung disease characterized by persistent airflow obstruction and chronic respiratory…
Biliary epithelial cells were found to actively prevent the progression of liver fibrosis
Many liver diseases have a common feature: fibrosis, the progressive accumulation of scarring in liver tissue. Those scars (the liver’s response to sustained damage or attack) can prevent the organ from functioning properly. Fibrosis affects millions of people worldwide and is a crucial step in the progression to cirrhosis, a fatal condition that can develop into liver cancer. Now, a new study by the National Cancer Institute (CNIO) natural metabolismidentified an important mechanism in the development of liver fibrosis. This discovery represents a further step towards developing personalized treatments that can help prevent its progression. More than just carrying bile…
Why do some dreams feel vivid and real while others are confusing or hard to remember? New research from the IMT School of Advanced Studies Lucca suggests the answer lies in a combination of individual characteristics and common life experiences, both of which influence what we see and feel during sleep. This study communication psychologyexamined more than 3,700 reports describing both dream and waking experiences from 287 participants aged 18 to 70. Participants recorded their daily experiences over a two-week period. At the same time, researchers collected detailed data on sleep habits, cognitive skills, personality traits, and psychological profiles. AI…
GSK’s Tesaro unit has dealt a blow to its legal battle with Jemperli developer AnaptysBio, with a Delaware court dismissing GSK’s breach of contract claims ahead of a trial scheduled for July. The latest information comes from the Delaware Court of Chancery, which rejected Tesaro’s claims that AnaptysBio breached the Jemperli license agreement between the two companies, meaning that GSK’s request for a reduction in royalties to AnaptysBio was also dismissed. Dan Faga, CEO of AnaptisBio, said in a statement that the decision “confirms what we have argued from the beginning: Tesaro’s anticipatory breach claims are without merit and this…
Stay ahead in medical research by tracking 299 new US clinical trials registered in April 2026 alone. Discover pivotal phase 3 trials, cancer breakthroughs, and AI-driven advances shaping the future of healthcare.
Human cells adapt to ever-changing conditions while maintaining the internal state necessary for survival, but exactly how cells achieve both adaptability and stability remains unclear. Researchers, including those at the University of Tokyo, have used a light-based technique called Raman spectroscopy for the first time to create a snapshot of the entire protein landscape inside E. coli cells in a non-destructive way. Analysis of the data allowed the team to predict how protein abundance would change under certain conditions. This was previously only possible by extracting the target protein. This allowed us to observe how the abundance of different proteins…
Recent research published in evolution and human behavior We present evidence that the social benefits of playing games are highly dependent on circumstances such as the player’s skill level and the risks present in the environment. Scientists use computer simulations to suggest that while playing games may not immediately lead to new friendships in a low-risk laboratory setting, games may have evolved as a way for early humans to identify highly skilled allies for dangerous missions. Playing and gaming are universal human activities, but they differ in important ways. Play involves spontaneous activity without a specific purpose, and is common…
Scientists reported today (April 27, 2026) that the brain is more mechanically connected to the body than previously realized. natural neuroscience. Through studies using mice and simulations, researchers have discovered a potential biological mechanism underlying why exercise is thought to be good for brain health. Contractions in the abdomen squeeze blood vessels connected to the spinal cord and brain, allowing organs to move gently within the skull. This shaking allows surrounding cerebrospinal fluid to flow more easily over the brain, potentially washing away neurological waste that can cause problems with brain function. Patrick Drew, a professor of engineering science and…