Author: healthadmin
Elevated lipoprotein(a) (Lp(a)) is an independent genetically determined risk factor for atherosclerotic cardiovascular disease (ASCVD), and its levels above 50 mg/dL affect 20–30% of the world’s population. Despite its therapeutic limitations, interest in Lp(a) is increasing due to its prognostic value and the emergence of targeted therapies. However, with the increase in guideline-based Lp(a) testing, clinicians’ responses to elevated concentrations remain unclear, especially in the absence of guideline-based treatment indications. In a new study and presentation at the American College of Cardiology, researchers found that elevated Lp(a) was associated with earlier and more frequent initiation of preventive drug therapy. These…
With Kerendia’s new Phase 3 victory, Bayer is one step closer to bringing this powerful drug to a wider range of chronic kidney disease (CKD) patients. Kelendia, also known as Filenone, met criteria in Bayer’s late-stage FIND-CKD study in nondiabetic adults with CKD, enabling the study to meet its primary endpoint, the company announced Monday. In this trial, Bayer’s drug helped patients chart a statistically significant and clinically meaningful reduction in renal function decline compared to placebo, as measured by the slope of estimated glomerular filtration rate (eGFR), which is used as a surrogate endpoint for clinical renal outcomes and…
Bread has been a staple food for thousands of years, and sourdough is experiencing a resurgence in popularity. Many people appreciate its natural ingredients, nutritional benefits, and unique flavor. However, the biological process behind sourdough fermentation remains surprisingly complex. What exactly happens during this fermentation, and how does wheat fiber affect the final quality of the bread? These questions guided Victor González Alonso’s doctoral research at the Vrije Universiteit Bruxelles (VUB) to study how a particular wheat fiber called arabinoxylan acts during sourdough fermentation. “Wheat accounts for the majority of calories and fiber consumed in Europe, and arabinoxylan plays an…
Get the health information and medications you need every weekday with STAT’s free newsletter Morning Rounds. Sign up here. good morning. Did you see the Oscars? We’ll send you tips on trending information and trending health news. (email protected) Transforming organ transplantation When you imagine what an organ transplant is like, you probably picture a medical worker holding onto an igloo cooler, fresh from a helicopter. People of a certain generation may perhaps imagine the classic scene from One Tree Hill, where one of those workers trips and Dan’s heart slides across the hospital floor and is eaten by the…
Although mummification has fascinated historians and scientists for centuries, many details about how ancient Egyptians preserved their dead remain unknown. A new study has found that the distinct musty odor of mummified bodies contains valuable clues about how these elaborate burial rituals were carried out. A study led by chemists at the University of Bristol has found that the odor associated with mummies is not simply a result of aging or decomposition. Instead, it reflects the complex mix of substances used during embalming, as well as the preservation fabrics and materials wrapped around the corpse. Taken together, these remaining chemical…
When inflamed areas of the intestine form scar tissue, the space within the intestinal lumen becomes smaller and more restricted, causing symptoms of intestinal obstruction. Currently, there are no drug treatments available for this complication. As fibrosis worsens, surgery eventually becomes the only option. Researchers have found that the greatest accumulation of scar tissue occurs in the submucosa (the layer of tissue beneath the lining of the intestine). This indicates that the submucosa may be the starting point where scarring begins. The inflammation that characterizes Crohn’s disease causes clusters or aggregates of immune cells to form in the submucosa. Using…
A large-scale computational study by researchers at the University of Jyväskylä (Finland) predicted that gold nanoclusters can selectively recognize chiral biomolecules. This property could be useful in detecting certain diseases directly from blood samples. Gold nanoclusters are atomically precise nanostructures with sizes of a few nanometers. They contain a metallic gold core, protected by a layer of organic ligand molecules. The chemical nature of the ligand molecules determines the solubility of the cluster in different environments and enables the functionality of the cluster’s outer organic surface and its interaction with the environment. Helical surface allows recognition of helical biomolecules The…
Climate change is fueling a public health emergency with rising heat deaths, air pollution, and vector-borne diseases in urban areas. Discover adaptation gaps and sustainable strategies for resilient cities.
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New research published in Personality and Social Psychology Bulletin It suggests that people always underestimate how much influence they have over their lovers and friends. This misperception tends to be stronger for people who are highly focused on protecting themselves and maintaining control, providing evidence that personal insecurities shape the way we view our intimate relationships. By recognizing this hidden influence, individuals may find healthier ways to communicate and resolve conflicts with loved ones. In psychological research, power is defined as the perceived ability to guide mutual decisions and meet personal needs rather than simply controlling others. Previous research has…