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Author: healthadmin
ELRIG, a volunteer-led nonprofit organization dedicated to the global drug discovery community, today announced Drug Discovery USA 2026. The inaugural event, to be held June 16-17 at Pfizer in Cambridge, Massachusetts, will provide the drug discovery community in Europe and the United States with an opportunity to connect and discuss new multifunctional small molecules and novel biological modalities against difficult-to-drug targets. ELRIG has appointed Professor Aled Edwards (Structural Genomics Consortium), Ph.D. Mariya Tadin Straps (Pfizer) and dr. Swarna Balasubramanian (AstraZeneca) As a conference director, you will help put together a bespoke scientific program and secure top speakers from across academia…
In the deserts of southeastern Arizona, an amazing scene unfolds outside the nest of a tiny stone ant. A much larger harvester ant stands nearby with its serrated jaws open, looking defenseless. But instead of attacking, the smaller ants climb on top of the larger ants and begin licking and nibbling their bodies. Scientists say this is the first known example of an ant species scavenging much larger ants. This act was reported in this week’s magazine ecology and evolution And it was observed by entomologist Mark Moffett, a research associate at the Smithsonian National Museum of Natural History. He…
Loneliness affects memory in older people, but does not accelerate mental decline over time, data from a major European study that followed more than 10,000 people over seven years suggests.Participants who reported higher levels of loneliness performed worse on memory tests at the beginning of the study period. However, the ability of people who felt lonely to recall information declined over monitored time at the same rate as that of participants who did not feel lonely.Research results published in peer-reviewed journals aging and mental health, This comes from an analysis of the Survey of Health, Aging and Retirement in Europe…
Although SARS-CoV-2 rarely reaches the placenta early in pregnancy, it still destroys early pregnancy immunity.
A large study of early pregnancy found little evidence that SARS-CoV-2 commonly infects placental tissue, but also showed that even limited virus presence can reshape immune signaling at the site where pregnancy begins. Research: Despite limited detection of the virus in placental tissue, SARS-CoV-2 infection during the first trimester causes severe immune dysregulation at the maternal-fetal interface. Image credit: Kateryna Kon / Shutterstock Recent research published in journals nature communications suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely undetectable in placental tissue during the first trimester, suggesting that efficient intrauterine infection is unlikely during early pregnancy despite…
An aortic aneurysm is characterized by an abnormal enlargement of the aorta, the main artery responsible for carrying blood away from the heart. Rupture often leads to sudden death, and there are currently no effective drug treatments to halt the progression of the disease.Researchers at Japan’s Nagoya University have found that aortic aneurysms are associated with clonal hematopoiesis, an age-related process in which blood-forming stem cells acquire genetic mutations. Their findings were; clinical research journalsuggests that commonly used osteoporosis drugs may slow or stop aneurysm progression.Currently, surgery is the only definitive treatment for aortic aneurysms. The surgical decision is determined…
Thirty years of research suggests that when children are exposed to parental depression may be as important as whether they are actually exposed to depression, with pregnancy emerging as a key period for maternal influence and a key period for paternal influence. Study: Timing of exposure to parental depression from pregnancy to adolescence and adult offspring’s mental health. Image credit: N Universe / Shutterstock In a recent comprehensive longitudinal study published in JAMA network openresearchers analyzed data from more than 5,000 adult children to investigate whether the timing of a child’s exposure to parental depression is associated with mental health…
Travele receives breakthrough rare disease approval, charting path towards Filspari’s $3 billion US opportunity
With the path to a blockbuster product in sight, Travele Therapeutics is ready to hit the ground running following Monday’s breakthrough approval of Filspari for focal segmental glomerulosclerosis (FSGS). The company said in a post-approval presentation that Filspari is the first product approved for a rare kidney disease and is poised to reach more than 30,000 eligible FSGS patients. Building on Filspari’s experience in greenlighting IgA nephrography (IgAN) in 2023, Travelere boasts a “ready-to-execute” commercial platform that can support “long-term, sustainable revenue growth,” the company said. Combined with the IgAN population already covered by the drug, Filspari now has the…
Cuba could break US energy blockade with $8 billion investment in renewable energy, think tank says | Cuba
Cuba could break America’s devastating energy blockade forever with just $8 billion in renewable energy investments. And the rest of the world will have to pay the price.These are the bold claims of a think tank’s analysis of the beleaguered socialist republic’s energy policy, which argues that Cuba can show its Caribbean neighbors a path to a green energy future.Just $8bn (£5.9bn) could fund the build-out of enough renewable energy to meet 93.4% of Cuba’s electricity generation needs, the report claims. For less than $20 billion, Cuba could become the first Caribbean country to have an entirely renewable energy grid.The…
This Mediterranean-style diet is associated with a slower rate of brain volume loss as we age.
A Mediterranean diet rich in olive oil, fish, vegetables, and legumes has long been associated with improved heart health. Brain-focused dietary variations are receiving scientific attention, with growing evidence suggesting they may support brain health as we age. It’s called the Mind Diet. The name stands for Mediterranean Dash Intervention for Neurodegenerative Delay, but more important than the acronym is what it actually contains. It includes plenty of green vegetables, beans, whole grains, nuts, berries, poultry, and fish, uses olive oil as the main cooking fat, and includes limited amounts of red meat, butter, cheese, fried foods, and sweets. It…
Lilly has been directed to gather more safety information for obesity product launch Foundayo
Even as Eli Lilly embarks on the launch of its next big obesity drug with Foundayo, FDA documents regarding the oral treatment indicate that concerns remain about multiple “unanticipated and serious” risks potentially associated with the drug. In the FDA’s approval letter (PDF) for the GLP-1 pill Foundayo, the agency ordered Eli Lilly to obtain more information about the drug’s potential association with serious cardiovascular events and drug-induced liver damage. Additionally, the agency would like to learn more about the delayed gastric emptying associated with this drug and its potential effects in breastfeeding women. In evaluating the drug data, the…