Groundbreaking new HIV vaccine shows unprecedented success in primates, data reveals nature The findings suggest that the vaccine has the potential to protect humans from HIV infection and the development of AIDS.
The vaccine was developed through a 14-year collaboration led by scientists at the La Jolla Institute for Immunology (LJI) and the Scripps Research Institute.
”This is one of the Apollo lunar exploration projects, with extraordinary goals and requiring the team to make countless discoveries and inventions along the way.” said LJI Professor and Chief Scientific Officer Shane Crotty, Ph.D., who led the study with Scripps Research Professor William Sieff, Ph.D.
Highlights:
- Researchers have developed an HIV vaccine that trains immune cells to overcome HIV defenses.
- The new HIV vaccines work by prompting the body’s immune system to produce large amounts of “broadly neutralizing” antibodies, which are rarely seen.
- In recent preclinical trials, this vaccine produced the highest HIV protective antibody response ever seen in primates.
- This study suggests that a new vaccine may protect humans from HIV infection and the development of AIDS.
sauce:
La Jolla Immunology Institute
Reference magazines:
Steichen, J.M.; Others. (2026) Vaccination induces antibodies that broadly neutralize HIV in primates. Nature. DOI: 10.1038/s41586-026-10837-5. https://www.nature.com/articles/s41586-026-10837-5-
