Author: healthadmin
For more than a decade, Hino Motors Corporation imported and sold more than 105,000 vehicles and engines with misleading or fabricated emissions data until an inspection by the Environmental Protection Agency uncovered an emissions fraud scheme. The lawsuit requires the Toyota subsidiary to plead guilty and agree to pay more than $1.6 billion in fines over five years and forfeit $1 billion in profits from illegal sales. The EPA touted the case Monday in its Enforcement and Compliance Assurance Results for the fiscal year ending Sept. 30, 2025, and claimed in a press release that the agency closed more cases…
Researchers at Oregon Health & Science University have developed a new molecule that may open the door to treating difficult cases of triple-negative breast cancer. Triple-negative breast cancer is a progressive disease for which there are currently few effective treatments. In a study published in a journal cell report medicineThe research team describes how an experimental molecule called SU212 blocks an enzyme that plays a key role in cancer progression. The findings came from experiments using humanized mouse models designed to mimic human disease. “This is an important advance in the treatment of triple-negative breast cancer,” said lead author Dr.…
CVS Health is investing in digital health and patient engagement technology across the enterprise, including a partnership with Simile to leverage “agent twins” to test and pilot new programs. The company built these digital twins based on 2.9 million agreed responses from a group of more than 400,000 people, representing responses across more than 200 behavioral scenarios. This allows the AI version to act as an accurate stand-in for the people it is based on. By deploying these digital agents, the company’s developers can test workflows, messages, and other services and receive feedback that reflects the behavior of real people.…
Sandoz didn’t mince words about the huge but largely untapped opportunity facing biosimilar makers, as dozens of branded drugs edge toward the patent cliff over the next decade. Now, as part of its efforts to take full advantage of what the company recently referred to as a potential “golden decade” of affordable medicines beyond 2030, Sandoz is further focusing on its biosimilars business with plans to launch a specialized division that will operate separately from the rest of the company’s small molecule generics division. The new biosimilars division will focus on the development, manufacturing and supply of mimicking biologics and…
A recent analysis of more than 200,000 people found that the relative length of the index and ring fingers was associated with sexual orientation. This study suggests that the hormones a fetus is exposed to in the womb determine its physical development and who a person is attracted to later in life. These results were recently published in the journal frontiers of psychology. Before birth, the developing fetus is exposed to varying levels of sex hormones. These hormones, such as testosterone and estrogen, play a central role in shaping the body’s physical differences. They also help regulate how genes are…
AbbVie CEO Robert Michael will be paid $32.5 million in 2025, his second year on the job, a significant 75% increase from his first year, solidifying his position as one of the highest-paid executives in the biopharmaceutical industry. Michael is the second CEO at AbbVie to take over the top job at the Illinois drugmaker after Richard Gonzalez’s 11-year tenure as CEO ends in 2024. Michael, a longtime AbbVie executive, has picked up immediately where Gonzalez left off by refocusing the company’s flagship immunology portfolio on growth engines SkyRigi and Rinvoke following the loss of exclusivity for long-time top seller…
Serious diseases that affect the transparent part of the eye called the cornea are very difficult to treat because this structure has no blood vessels and little ability to regenerate or repair. Many patients with serious corneal conditions can only be treated with a transplant, in which the damaged cornea is removed and replaced with a healthy cornea from another person who has donated the organ. Now, researchers from the Tissue Engineering Group of the Department of Histology, Faculty of Medicine, University of Granada, and the ibs.GRANADA Biomedical Research Institute have created highly biocompatible, resistant, and transparent corneal implants from…
A new biotechnology company created through an Australian-Danish partnership will accelerate treatments for children and adults with heart disease. The company aims to use cell therapy to conduct human clinical trials within three to five years. Launched today, Ibnova Therapeutics is the result of a world-first collaboration between Melbourne’s Murdoch Children’s Research Institute (MCRI) and Brisbane’s QIMR Berghofer. Within MCRI, this research is supported by the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW). The center is headquartered in Copenhagen and has research hubs at the University of Copenhagen, Leiden University Medical Center in the Netherlands, and MCRI. Denmark-based…
A new study led by researchers at VIB and the University of Leuven shows that immune cells called microglia may actively promote plaque formation in Alzheimer’s disease, challenging the long-held view that these cells act only as defenders against plaque buildup. The results of this study were recently published in PNAS. “Most studies suggest that microglia are there to cleanse the brain and remove amyloid plaques. What we found is that microglia are actually part of the problem. Microglia produce plaques,” said Professor Joost Simkowitz, co-senior author of the study from VIB-KU Leuven Neuroscience Center. “Plaque was thought to aggregate…
As the population ages, the need for better tools to diagnose and monitor Alzheimer’s disease (AD), the most common cause of dementia, has never been more urgent. The disease is characterized by a gradual loss of nerve cells, known as neurodegeneration, which begins years before obvious symptoms appear. One way to detect this damage is to look for signs of nerve cell damage. An important new biomarker of neurodegeneration is neurofilament light chain (NfL), a structural protein component of large nerve fibers. When neurons are damaged, NfL escapes into the cerebrospinal fluid and eventually into the bloodstream, providing a gateway…