Author: healthadmin
A randomized trial conducted by the Oncology Clinical Trials Alliance with support from the National Cancer Institute found that duloxetine, a drug commonly used to treat chronic pain and mental illness, did not prevent nerve damage caused by chemotherapy in colorectal cancer patients. The primary analysis of Alliance A221805 is JCO Advances in Oncology. Oxaliplatin is a standard chemotherapy drug used to treat colorectal cancer, but it can often cause peripheral neuropathy and can have permanent side effects that cause numbness, tingling, and pain in the hands and feet. Duloxetine is often prescribed for chronic painful conditions such as osteoarthritis…
A more powerful flu shot may do more than prevent infection. New research suggests it may slightly lower the risk of Alzheimer’s disease, especially in older women, providing new insights into brain health and prevention. Study: Risk of Alzheimer’s dementia after high-dose versus standard-dose influenza vaccination. Image credit: Galina Sharapova/Shutterstock.com Dementia affects approximately 57 million people worldwide and is an incurable disease, highlighting the need for low-cost prevention strategies. In recent research, Neurology sought to determine whether high-dose influenza vaccines are associated with a reduced risk of Alzheimer’s disease compared with standard-dose vaccines and to identify gender-dependent differences in efficacy.…
Explore the profound threats of climate change and pollution to human health, from rising heat-related deaths to expanded diseases, and discover sustainable urban planning solutions for resilience.
A large, long-term study led by researchers at Cedars-Sinai University of Health Sciences suggests that some drugs commonly prescribed to treat irritable bowel syndrome (IBS), including antidepressants, may be associated with a small but measurable increased risk of death. Survey resultswas published in communication medicineis based on nearly 20 years of electronic health records of more than 650,000 U.S. adults with IBS, making it the largest real-world study to examine the long-term safety of IBS treatments. IBS is a chronic gastrointestinal disease that affects approximately 10% of the U.S. population. There is no cure, but dietary modifications, behavioral therapy, and…
New single-cell technology gives scientists the clearest view yet of immune cell behavior, capturing not only their genetic intent but also their real-time activity. Simultaneous RNA and protein measurements reveal cytokine activity more precisely and strengthen the basis for understanding cancer, inflammation, and treatment resistance. Published in the April 8th issue scientific reportthis discovery could ultimately sharpen the design of immunotherapy and improve prediction of patient response. Researchers at the Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, in collaboration with collaborators at the University of California, San Francisco and the Helen Diller Family…
Insmed’s Brin supplement has failed for the second time in four months in a mid-term trial aimed at expanding its use to new indications. New Jersey Biotechnology, Inc. has revealed that a Phase 2B study of Brin supplement in adults with moderate to severe hidradenitis suppurativa (HS) failed to meet its primary or secondary endpoints in either the 10 mg or 40 mg once-daily groups. Due to this result, the company will terminate the program. The debacle comes after Insmed reported the failure of another Brin supplement trial testing a first-in-class dipeptidyl peptidase 1 (DPP1) inhibitor in patients with chronic…
New research published in developmental science This suggests that the act of giving to others, even at a very young age, is inherently rewarding for humans. Scientists have found that young children express more happiness when they share a snack with someone else than when they receive a treat themselves. This provides evidence that human cooperation is driven by natural emotional rewards from prosocial behavior, which refers to actions aimed at benefiting others. Across many different cultures, people routinely share their resources with friends and strangers. These acts of generosity often come at a personal cost, from providing food to…
Get the health information and medications you need every weekday with STAT’s free newsletter Morning Rounds. Sign up here. good morning. We have prepared some fun programming notes for you. “First Opinion Podcast” is back! This season focuses on the intersection of culture and medicine, starting with an episode about sports betting. Also, to spice things up around here, we’re rolling out new layouts for certain articles, starting with this morning’s great article by Jason Mast. 20 Years of Quest and Duchenne’s Progress Debra Miller’s son Hawken was 7 years old when he was diagnosed with Duchenne muscular dystrophy. A…
When Sean Brown opened an urgent care clinic in a remote town in Michigan’s Upper Peninsula, he never thought about performing abortions. But she never expected Marquette’s family planning organization to close last spring. Approximately 1,100 patients used the clinic each year for cancer tests, IUD insertions, and medical abortions. There are currently no other in-person resources for abortions in the area. “It’s cordoned off for 500 miles,” Brown said. So the doctor, who calls herself “personally pro-life,” added medication abortions to her already busy practice at Marquette Medical Urgent Care, which treats a steady stream of children with the…
Recent research published in psychological science This provides evidence that people naturally absorb its underlying rules simply by listening to music over a lifetime. The findings suggest that both trained musicians and people with no musical background use harmonic context in strikingly similar ways to predict and remember musical patterns. Scholars have long debated whether formal training is necessary to understand music’s deeper harmonic framework. Just as language is structured into words and sentences, music is organized into layers of notes, phrases, and sections. Some experts believe that understanding this organization requires explicit instruction in music theory. Other scientists argue…