Author: healthadmin
As many people age, they notice the familiar change in their waistline that gradually expands, even if their overall weight doesn’t change dramatically. This increase in abdominal fat is more than just a cosmetic issue. Excess belly fat is associated with slower metabolism, accelerated aging, type 2 diabetes, heart disease, and other chronic health problems. Scientists have long known that body composition changes with age, but exactly why fat is more likely to accumulate around the midsection remained unclear. Now, City of Hope researchers have identified what may be the main biological cause of age-related belly fat. Their findings were…
A new commentary published in the Journal of the Royal Society of Medicine warns that the current risk-based regulatory approach to artificial intelligence (AI) in healthcare is insufficient to protect patients and could lead to over- or under-treatment and even discrimination against patient groups. The authors found that although AI and machine learning systems can improve clinical accuracy, concerns about their inherent inaccuracy, opacity, and potential for bias remain, and are not adequately addressed by current regulatory efforts introduced by the European Union’s AI legislation. The AI Act, passed in 2025, classifies medical AI as “high risk” and introduces strict…
The development of a pioneering gene therapy to treat a devastating rare immune disease led by UCL scientists is about to move to the next stage following promising early preclinical studies. CTLA-4 deficiency is a rare disease of white blood cells known as regulatory T cells, which normally help regulate the immune system, and effector T cells, which protect the body from repeated infections and cancer. This is caused by the lack of the CTLA-4 protein, which is produced by a specific gene. Most people have two functioning copies of the gene, but people with the disease have only one…
Background and purpose In the United States, digital pathology (DP) is moving from an adjunct technology to an enterprise diagnostic platform. Despite accelerating clinical adoption, many laboratories face persistent barriers such as high capital and operating costs, workflow disruptions, interoperability challenges, and complex regulatory and reimbursement environments. This narrative review focuses on defining and operationalizing an organization’s artificial intelligence (AI) readiness for safe and sustainable adoption and proposes a practical lifecycle framework for implementing and sustaining a DP program. method We performed a targeted narrative review based on PubMed/MEDLINE and Google Scholar searches for English-language publications from January 1, 2014…
Background and purpose Acute leukemias with chimeric fusion genes involving FET (FUS, EWSR1, TAF15) family proteins and ETS (E26 transformation-specific)-like transcription factors often exhibit unique clinical and pathological features. This mini-review focuses on fusion sarcoma (FUS) or Ewing sarcoma breakpoint region 1 (EWSR1)gene. method An extensive literature review of reported cases of acute leukemia was conducted. FUS or EWSR1. Introducing details and summary information of reported cases. result Rare cases of acute leukemia are found to harbor one of the following: FUS or EWSR1 Genetic rearrangements with ETS or non-ETS proteins as partners exhibit heterogeneous clinical and pathological features. people…
Dr. Karishma Chhabria Unruh, assistant professor of public health at the University of West Florida, has been awarded an approximately $825,000 grant through the Florida Cancer Innovation Fund to lead a statewide effort focused on improving the health and well-being of breast and prostate cancer survivors. This award is one of the largest externally funded research grants ever received by an assistant professor within Maryland’s Usha Kundu College of Health and represents an important milestone for both Dr. Chhabria Unruh’s research program through the Integrated Mental Health and Population Analysis for Clinical Translation (IMPACT Lab) and UWF’s growing research enterprise.…
For female health care providers, Dobbs The decision to revoke abortion rights was not just an abstract political event. It has changed the legal and professional environment in which patients are cared for. ” Hilary Izatt, Assistant Professor of Political Science, Binghamton University, State University of New York Although previous research suggested that physician turnout was lower than the general public, a recent study using voter files found that physicians voted at a relatively high rate in 2020 and 2022. Question: Did the 2022 U.S. Supreme Court decision encourage more active involvement of women health care providers…
Exposure to a mixture of toxic and essential metals during early in utero development and shortly after birth is associated with subsequent behavioral problems and physical changes in the brain. Researchers used naturally shed baby teeth to track weekly exposure to metals, revealing specific time windows when the developing brain is most vulnerable to these elements. The study was published in the journal Science Advances. Mental health conditions such as depression, anxiety, and attention disorders affect many adolescents around the world. These conditions are caused by genetic risk factors, but are also shaped by the environment during early development. Medical…
Recent research published in Journal of social and personal relationships provides evidence that both having a happy romantic relationship and feeling financially secure independently contribute to a person’s overall health and well-being. The authors found that satisfying relationships protect mental and physical health, regardless of a person’s objective income or education level. These findings suggest that public health efforts may benefit from treating social connectedness and economic security as two separate but equally important pillars of a healthy life. Human health greatly depends on the environment and social conditions in which the person lives. Two main factors known to influence…
Modern society’s body standards, which emphasize both thinness and physical muscle tone, encourage unhealthy exercise and eating habits in both men and women. Although both genders internalize these pressures from internet platforms to the same extent, the psychological pathways that lead to risky behavior differ by gender. A study detailing these patterns was published in the journal Sex Roles. Historically, researchers have assessed societal body standards as separate concepts for men and women. The classic cultural expectation for women was extreme thinness, prioritizing low body weight without emphasizing strength. What was expected of men was a very muscular and bulky…