Author: healthadmin

A new peer-reviewed paper calls for meaning, purpose and spirituality to be treated as core elements of lifestyle medicine, rather than optional add-ons. Because these directly impact a patient’s ability to adopt and maintain health-promoting behaviors. This paper, “Meaning, Purpose, and Spirituality in the Clinical Practice of Lifestyle Medicine,” grew out of the 2025 National Summit held by the American College of Lifestyle Medicine (ACLM) in collaboration with the Global Positive Health Institute and funded by the Ardmore Institute of Health. The summit brought together nearly 100 experts to translate decades of research into practical clinical guidance. The authors synthesize…

Scientists have identified two non-intoxicating compounds derived from cannabis that may help reduce liver fat while improving metabolic health. The compounds CBD and CBG appear to support the liver in two important ways. These increase the organ’s ability to store backup energy and restore the activity of cellular systems that break down harmful waste products. Combining these effects may provide new plant-based strategies to treat the most common chronic liver diseases worldwide. The study was led by Professor Joseph (Yossi) Tam, Dr. Riad Hinden, PhD student Radka Kočvarova, and Tam’s team at the Department of Pharmacy, Faculty of Medicine, Hebrew…

Nerve cells in the brain are constantly bombarded with information from various senses simultaneously. How can the brain prioritize what’s most important? Imagine a friend meeting you at the station and showing you the way home. You will have to find your own way back. After that, remembering only the smell of freshly baked bread at a kiosk or the noise of a construction site won’t help you find your way. So what happens in our brains when we have to prioritize among the large number of impressions we receive? In a new study published in the journal Nature Communications,…

In a groundbreaking study published in BME FrontierResearchers at the University of California, Los Angeles (UCLA), in collaboration with international partners, have developed a deep learning-based virtual multiplexed immunostaining (mIHC) method. This new approach enables the simultaneous generation of ERG, PanCK, and H&E images from label-free tissue sections, greatly improving the accuracy and efficiency of vascular invasion assessment in thyroid cancer. Traditional immunohistochemistry (IHC) techniques, which are crucial in the diagnosis of various cancers, require separate tissue sections for each staining, leading to increased cost, labor, and potential tissue loss. Additionally, these methods have section-to-section variability, which compromises diagnostic accuracy.…

Major depressive disorder (MDD) is one of the leading causes of disability worldwide, with approximately 30% of patients developing treatment-resistant depression (TRD) that does not respond adequately to conventional antidepressant treatment. Although ketamine has emerged as a fast-acting antidepressant for TRD patients, its underlying biological mechanisms in the human brain are still poorly understood, limiting efforts to optimize and personalize treatment. In a new study published in the journal molecular psychiatry On March 5, 2026, a research team led by Professor Takuya Takahashi from the Department of Physiology, Yokohama City University Graduate School of Medicine used an innovative positron emission…

Problems with blood iron levels and the body’s ability to regulate this important nutrient as a result of SARS-CoV-2 infection may be an important trigger for prolonged COVID-19 infections, a new study has found. The findings not only point to potential ways to prevent or treat the condition, but may also help explain why long-term, COVID-19-like symptoms are also common in many post-viral conditions and chronic inflammation. Estimates vary widely, but as many as three in 10 people infected with SARS-CoV-2 may develop a long-term coronavirus infection, with symptoms such as fatigue, shortness of breath, muscle pain, and problems with…

Big drug companies are aligning with President Donald Trump’s “most-favored-nation” (MFN) drug pricing policy, but the details of the negotiated concessions and their actual impact on drug affordability in the United States remain unclear. Now, as these most-favored-nation benefits come under increasing scrutiny from patient advocates and others, and on the heels of efforts by Democratic lawmakers to push for more details in late 2025, Democratic Sen. Ron Wyden (R-Ore.), ranking member of the Senate Finance Committee, is seeking answers directly from drug companies. Sponsored by six other Senate Democrats, Wyden sent 11 letters to as many drug manufacturers as…

More than 200 metabolic enzymes, many of which are normally responsible for generating energy in mitochondria, are also found directly on top of human DNA, according to research published today. Nature Communications. This study shows that different types of cells, tissues, and even cancers have unique patterns of metabolic enzymes that are compartmentalized within the nucleus and interact with DNA. This is the first evidence that human cells have what the study authors call a “nuclear metabolic fingerprint.” More research is needed to determine whether the enzymes catalyze reactions, turn genes on or off, or simply provide structural support, but…

The University of Barcelona is strengthening its position at the forefront of European research thanks to the strategic project “VISI-ON-BRAIN: Cutting-edge human in vitro and in silico biomedical tools for brain diseases”. This is a training and research program involving 15 postdoctoral researchers focused on developing a new generation of human models to advance research into complex brain disorders such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. An important aspect of this effort is that research moves away from animal models and into experimental (in vitro) and calculations (in silico) model.Professor Josep M. Canals of the UB School of…

Professor Chao Zhang’s team at Southern Medical University Pearl River Hospital has developed a novel DNA nanomachine-based drug delivery and release strategy to overcome chemotherapy resistance in small cell lung cancer (SCLC). The research team identified the PRMT1/SOX2 signaling axis as a key driver of chemoresistance in SCLC, and based on this mechanism they designed DNA nanomachines that can be temporally programmed to release drugs. By precisely targeting chemoresistant tumor cells, the nanomachines rapidly release stemness inhibitors followed by sustained release of the chemotherapeutic agent cisplatin, effectively reversing tumor stemness and significantly increasing chemotherapy sensitivity. Research background Chemotherapeutic resistance remains…