Author: healthadmin

Pulp damage caused by trauma or deep cavities often leads to inflammation, tissue necrosis, and ultimately loss of tooth vitality. In severe cases, bacterial invasion and a sustained immune response further compromise the pulp microenvironment and destroy the pulp’s natural repair ability. Although regenerative endodontic approaches aim to restore living tissue, achieving predictable biological repair remains difficult. Central to successful regeneration is the precise control of stem cell signaling pathways that coordinate cell proliferation, differentiation, and matrix remodeling. Among these, Wnt/β-catenin signaling plays a fundamental role in stem cell proliferation, differentiation, and tissue repair. However, the upstream molecular mechanisms governing…

Can smartphones and smartwatches help detect early signs of neurological and psychiatric disorders? Researchers at the University of Geneva (UNIGE) monitored a group of participants wearing connected devices and used artificial intelligence to analyze data such as heart rate, physical activity, sleep, and air pollution. Their findings show that connected devices can accurately predict emotional and cognitive fluctuations, opening new avenues for early detection of changes in brain health. This research npj digital medicine. Brain health, including both cognitive and emotional function, is one of the major public health challenges of the 21st century. According to the World Health Organization…

Carrum Health, which provides value-based specialty care to employers, has partnered with Virta Health on weight management. Virta offers virtual counseling, nutritional guidance, and medication management using GLP-1. Employers can customize Virta’s services based on their benefits. Meanwhile, Kalam has already undergone bariatric surgery to manage his weight. You can now browse and adjust members between the two as needed. “The goal was to ensure we took care of our members throughout their weight loss management protocol,” Matt Urey, Column’s chief commercial officer, told Fierce Healthcare in an exclusive upfront interview. “There is currently a lot of interest in the…

A study of infants in their first year of life found that infants in families where parents felt their income was insufficient to support the needs of their families were more likely to have delayed brain development. More specifically, on electroencephalography, these children showed a tendency for slower rates of change in alpha peak frequency, alpha power, and beta power. The paper is PNAS. During the first year of life, your baby’s brain grows faster than at any other time. This period lays the foundation for how a child will think, feel, and interact with others in the future. Most…

In BioNTech’s search for a new CEO, the German company is looking for a new leader with “late-stage development and commercial execution experience,” Chief Financial Officer Ramon Zapata said on its quarterly conference call, following the announcement earlier Tuesday that Ugur Şahin, MD, and his wife, CMO Ozlem Tureci, MD, would leave by the end of the year to start a new company. The company says it has several potential product announcements scheduled for the end of this “catalyst-rich year,” and Sahin said now is “the perfect time for the transition.” Analysts at Leerink Partners agreed, calling the transition a…

In the breakup between Dana-Farber Cancer Institute and Mass General Brigham, the two parties made a conscious decision to uncouple rather than an acrimonious divorce. At least for now. In a recent joint email to staff, the hospitals said leaders from both facilities met to discuss hiring physician assistants who are employed by Dana-Farber but contracted by Brigham to work in inpatient oncology. STAT+ exclusive story Already have an account? Log in This article is exclusive to STAT+ subscribers Unlock this article and get in-depth analysis, newsletters, premium events, and news alerts. Already have an account? Log in Individual plan…

The Food and Drug Administration on Tuesday approved a drug to treat a rare brain disease similar to autism, but retracted previous statements from top health officials that “hundreds of thousands” of children with autism could benefit from taking the drug. The drug leucovorin will be available for children and adults with cerebral folate deficiency, which limits the delivery of folic acid, a B vitamin, to the brain. This approval was given to GSK, the original manufacturer of Welcovorin, a branded version of Leucovorin, but the company discontinued production in 1997. The company does not intend to manufacture or sell…

Amid the company’s efforts to resolve issues raised during an FDA inspection early last year, Novo Nordisk’s Plainsboro, N.J., operations, which had already received an updated Form 483, was hit with the more serious consequences of a warning letter. Novo acknowledged the letter, available on the FDA’s website, in its own communiqué on Tuesday, emphasizing confidence that the letter would address the U.S. regulator’s concerns. The Plainsboro tangle began when the FDA first inspected Novo’s site, which serves as its U.S. headquarters, from Jan. 13 to Feb. 7, 2025, as part of a review of the company’s compliance with post-marketing…

Zaire-Calvin’s insurance check to rebuild his family’s fortune was just under $300,000, far less than the value of the property, which was about $2.1 million. His family had spread five homes across two lots in the leafy suburb of Altadena, California, until the Eaton Fire unleashed its fury, destroying both his and his mother’s homes and turning the tight-knit black homeownership enclave into a prime location for speculators. Even more tragically, this hell also took away his sister, Evelyn McClendon. Calvin, 48, said the past 15 months had been like a “war”, especially with his insurance company. She is also…

New research published in scientific report suggest that the relationship between young people’s cognitive ability and future socio-economic status is primarily driven by genes. The findings provide evidence that genetic factors play a greater role in educational and occupational success than environmental conditions. This underlying biology may help explain why some social interventions aimed at reducing inequality tend to be insufficient in the long term. Social scientists have spent decades understanding the psychological mechanisms that produce socioeconomic status. Obtaining an education and securing a job are the main ways young people earn a living and begin to establish themselves in…