Author: healthadmin

Sildenafil – the active ingredient also sold under the name Viagra – improves symptoms in patients with Leigh syndrome. This is currently cell This journal was co-authored by researchers from the Berlin Charité – Universitätsmedizin and a team from the Heinrich-Heine University of Düsseldorf (HHU), the University Hospital Düsseldorf (UKD) and the Fraunhofer Institute for Translational Medicine and Pharmacology ITMP in Hamburg. Leigh syndrome is a rare, previously untreatable metabolic disease that begins in childhood and causes severe neurological and muscular symptoms. In a preliminary study on six patients, sildenafil showed a positive effect on the course of the disease.…

According to recent reports from multiple institutions pro swan The time of onset of hearing loss is an important determinant of patient confidence and self-reported sound localization ability (the ability to recognize and locate objects in the environment), even in people who use hearing aids or have received visual rehabilitation training, according to a study led by the Multisensory Laboratory at the Johns Hopkins Wilmer Eye Institute. The research, supported by the National Institutes of Health, focuses on the factors that shape how people with dual sensory loss (combined loss of hearing and vision) interact with their environment and identifies…

Where a woman lives has a significant impact on whether breast cancer is diagnosed early or at a later stage, according to a national analysis published in . Journal of the American College of Surgeons (jacks). The researchers found that there were significant geographic differences within rural areas across the United States, and that race and insurance status also had a significant impact on the stage of a woman’s breast cancer at the time of diagnosis. Geographical disparities were very pronounced. We found that among different rural areas across the country, a woman’s geographic residence was one of the…

With an impressive victory over blockbuster products in three head-to-head psoriasis clinical trials, UCB’s Bimzelx has conquered another strong product in psoriatic arthritis (PsA), AbbVie’s Skyrizi. The Belgian company said the Phase 3b study in 553 adults with active psoriatic arthritis met its primary objective, showing Bimzerx had a “statistically significant superiority” over Skyridi in reducing disease activity as measured by the ACR50 endpoint at week 16. ACR50 is a composite efficacy measure designated by the American College of Rheumatology that indicates a 50% or greater improvement from baseline in the number of tender or swollen joints, in addition to…

As many drug companies tally their CEO compensation for 2025, another major drug executive has amassed more than the $30 million threshold. Johnson & Johnson CEO Joaquin Duato will earn approximately $32.8 million in salary in 2025, significantly more than the $24.3 million he earned in 2024. Duato took the helm as J&J’s CEO in early 2022. By the numbers, Duato received a $1.6 million salary, the same salary he earned in 2024, and nearly $21 million in stock and option awards. Non-equity incentive compensation for the period was approximately $4.3 million. Duato collected about $600,000 in the “other compensation”…

Skyhawk Therapeutics has appointed Aaron Debs as chief commercial officer, securing the expertise of the executive who oversaw products such as Austed while at Teva. The company shared the news on the same day, saying Sunterra Pharmaceuticals also hired a new chief commercial officer. Boston-based Skyhawk has signaled it could win accelerated approval in Australia for its Huntington’s disease drug candidate SKY-0515 within 12 months. Skyhawk’s 2027 plans include launches in other markets, and the biotech company has begun preparations for commercialization, hiring Debs to lead the company. Debs previously served as chief operating officer and marketing officer for Teva’s…

A ban on disposable e-cigarettes in the UK could lead to young people switching to alternative products, including cigarettes, new research led by the University of Bristol has found. In response to growing concerns about e-cigarettes among young people, the UK government last year introduced a ban on disposable e-cigarettes (from 1 June 2025). The ban is aimed at curbing use by minors, but the impact it may have on the approximately 2.5 million adults in the UK who rely on disposable e-cigarettes is unclear. New qualitative research PLOS Global Public Health Today (March 11), young people revealed how they…

Photoreceptors are specialized cells in the eye that convert light energy into nerve signals. Several diseases that cause irreversible vision loss, such as age-related macular degeneration, retinitis pigmentosa, and retinal detachment, are associated with the death of photoreceptors. Although there are many molecular pathways that lead to cell death, there are also many molecular pathways that try to keep cells alive. In a new study published in cell death and diseasea research team at the University of Michigan has discovered that functional mitochondria are key to the recovery of dying photoreceptor cells. Apoptosis is the main pathway by which cells…

The relationship between social connectedness and cognitive performance is particularly complex during perimenopause, when women transition from the reproductive period to menopause. New research suggests that loneliness and social isolation are not only independently associated with declines in subjective cognitive function during perimenopause, but also show a joint relationship. The research results will be published online today. menopauseJournal of the Menopause Society. Perimenopause, which usually occurs between the ages of 45 and 55, is a time of many changes due to the gradual decline in ovarian function and fluctuating estrogen levels. Common physical symptoms include hot flashes and trouble sleeping.…

Countries that generate more electricity from wind, solar and other renewable sources will be better protected from global energy shocks, experts say, as escalating conflict in the Middle East disrupts global markets. The war has escalated since the United States and Israel launched attacks on Iran more than 10 days ago. Critical infrastructure in the region has come under attack and the risk of an Iranian attack has effectively closed the Strait of Hormuz, a vital waterway used to transport 20% of the world’s oil and gas. The disruption means fuel could be difficult to reach countries that rely on…