Author: healthadmin

A team from the University of Barcelona has designed an innovative compound with a pioneering mechanism of action for the treatment of Alzheimer’s disease and tested it in animal models. Unlike current drugs, which primarily remove beta-amyloid plaques that accumulate in the brain, this new experimental drug reprograms the neuroepigenome by correcting changes in gene expression that contribute to disease progression. The results of this study are molecular therapyopening the door to epigenetics-based therapeutic strategies to combat Alzheimer’s disease. The compound FLAV-27 represents an innovative and promising approach to Alzheimer’s disease, with the potential to modify the disease process as…

You’re reading the web version of DC Diagnosis, STAT’s twice-weekly newsletter about health and medical politics and policy. Sign up here to get it in your inbox on Tuesdays and Thursdays. Chelsea Handler has talked a lot about the “most toxic” house she bought from RFK Jr. and Cheryl Hines for about $6 million. Don’t forget to check out STAT’s Breakthrough Summit East today and send your new tips to: (email protected) Or Signal’s John_Wilkerson.07. rise from the ashes Democrats argue they have an opportunity to reinvent health care from the ground up because Republicans set it up long ago.…

To expand its reach in the ADHD market, Collegium Pharmaceutical has entered into an agreement to acquire Azstarys from Corium Therapeutics. The deal includes $650 million upfront and $135 million in potential milestone payments and gives Collegium its second branded ADHD drug, Azstarys, and its Jornay PM. Chempharm, a Florida pro-drug specialist, won FDA approval for Azstaris in 2021, two years after entering into a licensing agreement with privately held Corium, an affiliate of investment fund Garnet Point Capital. Collegium does not disclose sales figures for its drugs, but Collegium said it expects Azstaris to generate more than $50 million…

The first major update to strength training recommendations in 17 years sends a straightforward message. Even small amounts of strength training can improve strength, increase muscle size, increase power, and support overall body function. The latest guidance, published by the American College of Sports Medicine (ACSM) as a position stand, is built on 137 systematic reviews involving more than 30,000 participants. This makes it the most extensive, evidence-based resistance training recommendation to date. “The best strength-training programs are the ones you can actually stick to,” says Stuart Phillips, distinguished professor in the Department of Kinesiology and author of “Position Stand.”…

Almost one in two Americans has high blood pressure (also known as the “silent killer” because of its negative effects on the heart and blood vessels), but many people don’t know they have high blood pressure. In a study presented at the American College of Cardiology’s Annual Scientific Sessions (ACC.26), researchers report that high blood pressure-related heart disease is an increasing proportion of deaths among women ages 25 to 44, increasing from 1.1 to 4.8 deaths per 100,000 women in this age group between 1999 and 2023. High blood pressure damages the heart and is an indicator of heart disease…

Spending too much time looking inward can lead to higher levels of depression and anxiety instead of increasing your sense of well-being. A new review of past research has been published. current psychology Analyzing one’s own thoughts has been shown to have negative consequences for mental health, while not measurably increasing positive emotions such as self-esteem and life satisfaction. These results suggest that cultural background and the specific ways we measure introspection have a significant impact on how introversion affects our minds. Introspection is the internal process of examining one’s own thoughts, memories, feelings, and actions. Mental health experts see…

WASHINGTON (AP) – Twenty states and more than a dozen cities and counties sued the Environmental Protection Agency on Thursday, challenging the Trump administration’s reversal of scientific discoveries that were central to U.S. actions to regulate greenhouse gas emissions and combat greenhouse gases. climate change.rule finalized by EPA Last month, the 2009 agreement was canceled. discovery of danger Measurements of carbon dioxide and other greenhouse gases threaten public health and welfare. Discoveries made during the Obama era Legal basis for almost all climate regulations The Clean Air Act targets cars, power plants, and other sources of pollution that heat the…

AlphaSigma’s buzzer-beater bet on GSK’s prospects for rare liver diseases has paid off. Last week, the FDA issued its approval days ahead of schedule after signing a deal worth up to $690 million to acquire worldwide rights to the drug. The drug, approved under the name Lynavoy, is an ileal bile acid transporter inhibitor designed to alleviate multiple factors of chronic itch. With this approval, the medicine is in a position to offer treatment to the 89% of patients with primary biliary cholangitis (PBC) who experience cholestatic pruritus, an often debilitating itchy condition. The FDA approved the drug days ahead…

New research links high temperatures and air pollution to increased suicide risk.Nitrogen dioxide primarily affects suicide rates during winter reversals.This study revealed an interaction between heat, air pollution, and suicide mortality.Suicide rates have been rising for decades, and recognizing the effects of heat stress and air pollution can be helpful as policymakers and others seek tools to identify and protect those at risk. That’s according to a new study by a team at the University of Utah, which found a link between increased year-round heat and suicide risk, as well as specific risks from nitrogen dioxide during winter air inversions.…

Turquoise Health, a healthcare pricing and payment platform, has secured $40 million in Series C funding. The startup was founded in December 2020 to help patients understand the cost of medical services before they receive treatment. Patients can compare costs with Turquoise Health’s online search engine, and users can also research providers, services and quality of care. Executives have previously said the platform’s goal is to make shopping for health care as easy as buying a plane ticket. The company has evolved its business from analyzing medical pricing data to building a platform that centrally manages data, contract information, and…