Author: healthadmin
Curcumin, berberine, and other plant-based compounds have long been of scientific interest due to their anti-inflammatory and anticancer properties. However, a new study by researchers from the Wrocław University of Medicine and the University of Wrocław has shown that not all natural compounds work the same, and that strong anticancer activity does not necessarily go hand in hand with a good safety profile. The researchers compared five compounds: curcumin, berberine, biochanin A, cucurbitacin E, and CAPE (caffeic acid phenethyl ester), a component of propolis. They investigated how these substances affected fibrosarcoma cells and healthy muscle cells. cellular control switch This…
Artificial intelligence native platform Assured has secured $19 million in Series A funding to automate provider authentication and onboarding to AI agents. Insight Partners led the funding round, with participation from existing investors First Round Capital and Kindred Ventures. “Across healthcare, provider certification and enrollment remains some of the most difficult and costly parts of expansion,” Insight Partners Managing Director Teddie Wardi said in a statement. “Tools built for this category act as systems of record that leave the actual work to humans. Assured is the first platform to do the work itself. The shift from software that tracks processes…
Scientists at the University of Virginia Comprehensive Cancer Center have developed a promising new experimental approach to target glioblastoma, the most common and deadliest brain tumor. This approach has the potential to overcome many of the limitations of existing drug-based treatments. UVA’s Roger Abunader, MD, PhD, and colleagues have identified a “microRNA” that can simultaneously suppress multiple dysfunctional genes involved in glioblastoma formation and growth. Researchers are using a combination of brain-penetrating nanoparticles, focused ultrasound, and microbubbles to deliver miRNAs through the brain’s natural protective barrier, a barrier that typically impedes treatment of tumors and neurodegenerative diseases. This new…
Bunia, Congo – The Ebola outbreak in Congo has killed at least 999 people, according to official data released overnight on Wednesday, with the devastating toll in what is already being described as the fastest Ebola outbreak in history compounded by a strike by some health workers. As of Monday, the outbreak had recorded 2,473 infections and 999 deaths, according to the latest information from Congo’s Ministry of Health. At least 737 patients are currently in isolation and admitted to hospitals, the report said. The Ebola outbreak declared on May 15 is different from most previous Ebola outbreaks because there…
Scientists at the Johns Hopkins School of Medicine have discovered new evidence that small chunks of brain tissue grown from the cells of Alzheimer’s disease patients could help researchers predict how different patients will respond to medications used to manage psychiatric symptoms associated with Alzheimer’s disease. The study focused on lab-grown brain tissue called organoids. The discovery adds to the evidence that these miniature brain models may ultimately help scientists develop and select more precise treatments for specific groups of Alzheimer’s patients. Alzheimer’s disease is the most common dementia, affecting more than 7 million Americans. The researchers also discovered that…
Exposure to a widely used herbicide during the second trimester of pregnancy may increase the chance of premature birth, before 37 weeks, a new study shows. The investigation focused on glyphosate, the active chemical ingredient in professional Roundup products that are sprayed on commercial food crops such as grains and legumes, as well as residential gardens. Residues of this chemical have been found in cereals, snack foods, and fresh fruits and vegetables. The new study, led by researchers at New York University Langone Health, looked at 1,450 women and found that those with higher levels of glyphosate in urine samples…
A new randomized clinical trial suggests that singing therapy may be a more effective and attractive treatment option than standard breathing exercises for people with bloated stomach, a chronic gastrointestinal disorder that can have a significant impact on quality of life. The study will be published in the Journal of the American College of Gastroenterology clinical gastroenterology and hepatology; is the first randomized controlled trial to evaluate singing therapy for bloated stomach. In this condition, air repeatedly moves in and out of the esophagus instead of the stomach, causing rapid and excessive burping (sometimes hundreds to thousands of times a…
In a randomized clinical trial published in internal medicine journalingesting capsules containing fecal microorganisms from healthy donors helped treat symptoms of insomnia. One month after treatment, participants who received the fecal microbiota capsules had significantly improved sleep efficiency and decreased post-sleep awakenings, as measured by nocturnal polysomnography. Patient surveys also showed that sleep quality scores improved over two to six months in the intervention group compared to the placebo group. Our findings provide clinical evidence that targeting the gut microbiota may provide a promising new therapeutic strategy for chronic insomnia. This study also strengthens our understanding of the gut-brain…
Research suggests that more than half of children with autism spectrum disorder, a neurodevelopmental disorder, experience movement disorders. analysis in Developmental medicine and child neurology Sports-based interventions may improve motor skills in children with autism spectrum disorders, with martial arts and aquatic training showing the most consistent effects. This analysis is based on data from 11 clinical trials across a variety of sports. Martial arts consistently showed significant gains in balance, gross motor skills, and object control, with tai chi and kata programs being particularly effective. Underwater training demonstrated significant improvements in balance, motor skills, and object control abilities. The…
Cachexia, characterized by progressive muscle wasting, affects both humans and dogs with chronic diseases such as cancer. In recent research, molecular oncology found that low circulating levels of certain microRNAs (small non-coding RNAs that regulate gene expression) often indicate the presence of cachexia in older dogs. For this study, researchers analyzed blood levels of numerous microRNAs in 25 senior dogs. Reduced levels of miR-15a, miR-15b, miR-16, and miR-140 are indicators of cancer-related cachexia, with miR-16 being the most powerful individual marker. Gender-specific analysis revealed that miR-140, a microRNA with anti-inflammatory properties, was significantly lower in female dogs with cancer (mainly…