Author: healthadmin

With the green light already in place for obesity, Eli Lilly is moving forward with its newly launched Foundayo (orforglipron) for the treatment of type 2 diabetes, with the goal of creating an oral product to rival Novo Nordisk’s two GLP-1 tablets in both indications. Now, with results from three pivotal Phase 3 trials presented Monday at the American Diabetes Association’s 2026 Scientific Sessions, Lilly is setting its diabetes data squarely in the crosshairs of two of oral GLP-1’s biggest potential rivals. The most notable topic at the conference will undoubtedly be the results of Achieve-3, a head-to-head study in…

A meta-analysis of studies examining the association between spirituality and harmful use of alcohol, tobacco, marijuana, and other drugs found that higher spirituality was associated with a 13% reduced risk of harmful use across the drugs studied. Individuals who participate in a spiritual or religious community (defined as those who attend religious or spiritual services at least once a week) had an 18% reduced risk. The paper is JAMA Psychiatry. Harmful or dangerous alcohol and other drug (AOD) use refers to a pattern of drinking or drug use that increases the risk of physical, psychological, social, or legal problems. Dangerous…

Most breast cancers are exacerbated by estrogen. To combat recurrence of these cancers, clinicians treat patients with estrogen production inhibitors, such as letrozole. However, many patients do not adhere to this treatment due to negative side effects. Preclinical studies in rodents suggest that a drug called 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED), which delivers estrogen only to the brain, may be an effective and safe way to reduce these side effects. new JNeurosciResearchers led by Agnes LaCruz at the University of Massachusetts Amherst investigated how DHED works in older marmosets, a more advanced animal model than rodents. After treatment with letrozole, the research team…

AI has already brought positive results in the medical field and is expected to bring even more. But it’s important to proceed at a thoughtful and deliberate pace when implementing AI tools, especially in life-or-death medical settings, warns Shengpu Tang, assistant professor of computer science at Emory University. Tang et al. found flaws in many peer-reviewed studies that used an AI technique known as reinforcement learning to theoretically guide sepsis treatment. diary npj digital medicine published their findings. Through simulation experiments, they demonstrated problems with techniques commonly used for data preprocessing and indexing related to sepsis treatment. This flawed technology…

It’s a sign of the times that at this year’s American Diabetes Association (ADA) Scientific Sessions meeting in New Orleans, there was more talk about obesity drugs and pipeline programs than diabetes-specific treatments. At the event, a number of leading biopharmaceutical companies shared the latest information on next-generation medicines aimed at helping patients slim down and protecting them from various metabolic-related diseases. When it comes to big pharma and the incretin market, another sign of the times is that Eli Lilly has emerged as a “clear winner from ADA,” said Chun Huynh, a pharmaceutical analyst at RBC Capital Markets. “ADA…

A new research paper has been published in Volume 17. onco target June 3, 2026, titled “The anticancer effect of PCAI in pancreatic cancer cells involves enhanced activation of MAPK and PI3K/AKT pathways.” The study was led by first author Kweku Ofosu-Asante and corresponding author Nazarius S. Lamango of the Florida A&M University School of Pharmacy and Institute of Pharmaceutical Sciences at the Institute of Public Health in Tallahassee, Florida. Pancreatic ductal adenocarcinoma is one of the most lethal cancers, primarily due to the high frequency of KRAS mutations that promote tumor growth and treatment resistance. Although targeted therapies for…

A research team at the University of Minnesota Medical School has been awarded a five-year, $3.8 million grant from the National Institute of Allergy and Infectious Diseases to study the early immune response in the lungs and how it influences the outcome of tuberculosis infection. The research program, led by Monica Campo, MD, a physician-scientist at the University of Minnesota Medical School, focuses on how lung immune cells called macrophages influence the early stages of tuberculosis infection. Although tuberculosis begins in the lungs, little is still known about the earliest immune events that determine whether the infection is controlled…

The EU itself has called on other countries and regions to step up monitoring. “Due to the complex nature of ocean observations, no single country or region can observe the oceans alone. This has to be a global effort with diplomacy at the forefront,” said Costas Cadiz, European Commissioner for Oceans, at the Neptune Forum, an event on ocean exploration and diplomacy in Paris on Monday. Ocean Eye is part of the EU’s Oceans Agreement, a plan to improve the health of the oceans and boost regional ocean economic and security interests as human-induced climate change continues to disrupt ocean…

A new report in the American Journal of Human Genetics describes a new disease caused by a biallelic loss-of-function variant. TMEM63B A gene that causes severe lung disease. Researchers from Baylor College of Medicine, Texas Children’s Hospital, and collaborating institutions in Asia and Europe describe how five people in four unrelated families developed the disorder. Variants that lead to gain of function in one copy of TMEM63B The gene (heterozygous variant) has previously been associated with developmental delay and neurological conditions such as epilepsy. However, previous studies have not reported symptoms in patients with biallelic loss-of-function variants. In this variant,…

Recent research provides evidence that a seemingly trivial temporary delay in regular paychecks can increase women’s risk of intimate partner violence. This finding suggests that the emotional stress of straining household finances for extra days can negatively impact relationship dynamics. This study Journal of Health Economics. Intimate partner violence is a pervasive public health challenge in the United States. More than a third of women in this country have experienced physical violence, rape, or stalking by an intimate partner at some point in their lives. The effects of this violence go far beyond direct physical harm. Survivors tend to have…