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Author: healthadmin
As Gilead’s Trodelvy stumbles in first-line lung cancer, all eyes are on Merck, Arizona, and No. 1 rival
The race to bring TROP2 antibody-drug conjugates (ADCs) to first-line non-small cell lung cancer (NSCLC) patients has narrowed following another failure in a Phase 3 trial of Gilead Sciences’ Trodelvy. On Monday, Merck and Gilead announced they were discontinuing the Phase 3 Evoke-03 trial, also known as Keynote-D46, following the recommendation of an external data monitoring board. This study evaluated Trodelvy in combination with Keytruda versus Keytruda alone as first-line treatment for patients with PD-L1-high NSCLC. The companies said that although positive trends were observed in the trial, the endpoint of progression-free survival was not met in the final analysis.…
It turns out that the hidden heart disease trigger of sleep apnea syndrome lies in the intestines
Millions of people around the world have obstructive sleep apnea. Obstructive sleep apnea is a common disorder in which breathing is repeatedly interrupted during sleep. A new study in mice suggests that gut microbes and the compounds they produce may play a surprising role in protecting against some of the most serious conditions, including heart disease. The findings, presented at ASM Microbe 2026, point to potential new targets for the prevention and treatment of cardiovascular complications associated with sleep apnea. How sleep apnea syndrome affects the body Obstructive sleep apnea causes a person to stop breathing repeatedly throughout the night.…
Superheavy particles may help explain one of the most puzzling mysteries in modern astrophysics: the origin of the most energetic particles ever detected. Ultra-high-energy cosmic rays are particles that hit Earth from space with energies far exceeding those produced by human-made particle accelerators. Among the most unusual examples is the “Amaterasu particle,” detected by a telescope array in Utah in 2021 and named after the sun goddess in Japanese mythology. Its reported energy ranks it as one of the most powerful cosmic ray phenomena ever observed, placing it in the same rare category as the “Oh my God particle” recorded…
An online survey of Australian adults found that those with less secure attachment orientations as adults were more likely to report feeling more lonely. They also found that certain types of motivations for loneliness mediated the association between insecure attachment and loneliness. The paper was published in. Journal of social and personal relationships. Loneliness is a painful feeling that occurs when a person believes that their social relationships are fewer, weaker, or less satisfying than they would like. It is not the same as being physically alone, as a person can enjoy solitude without feeling lonely. Even when people are…
New research published in journal Environmental research: climate found that extreme heat is already impacting cancer patients’ ability to manage their daily lives, access care, and treatment-related decisions. The study, led by researchers from the Sylvester Comprehensive Cancer Center, Rosenstiel School of Ocean, Atmospheric and Earth Sciences, and School of Nursing and Health Research, part of the University of Miami Miller School of Medicine, highlights the need to incorporate environmental risks into cancer treatment plans, from clinical conversations and appointment planning to caregiver coaching and community support. The study, based on in-depth interviews with cancer patients in South Florida, which…
A new study suggests that eating more ultra-processed foods can make it harder to stay focused, even for people who eat a healthy diet, and may contribute to factors associated with dementia. Researchers from Monash University, University of São Paulo and Deakin University analyzed dietary and cognitive data from more than 2,100 middle-aged and older Australian adults without dementia. Their discovery is Alzheimer’s disease and dementia: diagnosis, evaluation, and disease monitoringJournal of the Alzheimer’s Association. Ultra-processed foods and attention span The study found that even small increases in ultra-processed food consumption were associated with measurable decreases in attention and mental…
Teresa is the lead writer for Morning Round, and her articles focus on gender-affirming care, reproductive health, and mental health. You can reach Theresa at signal theresagaff.97.Get the health information and medications you need every weekday with STAT’s free newsletter Morning Rounds. Sign up here. good morning. After much consideration, STAT made the decision to stick with “health care.” Two words. Sarah Mpo, STAT’s very thoughtful Director of Editorial Operations, explains the decision here. Her account collects readers’ opinions on this issue. I was particularly interested in the comments made by Karen Penner, a former editor of this newsletter, about…
Sexism is often a stronger predictor of political attitudes than a voter’s actual gender
Recent systematic reviews published in quarterly public opinion suggests that voters’ level of sexism is an important predictor of their political attitudes and vote choices. By analyzing nearly 100 previous studies, the study provides evidence that different types of prejudice shape everything from support for right-wing candidates to opinions on climate policy. The findings highlight how deeply held beliefs about gender roles continue to influence the contemporary political landscape. Michał Gurczynski, a postdoctoral researcher at the European University Institute in Florence, Italy, conducted the study to understand how pervasively gender discrimination influences political behavior. The 2016 US presidential election sparked…
summary The North Bay Parry Sound District Health Department has officially suspended water quality testing at public beaches. Instead of testing, the health department is updating public signage to warn swimmers of the dangers of poor water quality, such as heavy rain, murky water and large flocks of birds. Researchers and advocates say coastal water monitoring is important, especially as climate change increases the need to cool down in the water and makes it more dangerous due to algae blooms and pathogens. Kevin Marois didn’t know that the health unit that spans North Bay and Parry Sound, Ont., had stopped…
Chemicals introduced to repair and protect the Earth’s ozone layer may have caused unforeseen environmental problems. Some of the substances that have been replaced by ozone-depleting chemicals are now causing large amounts of persistent “permanent chemicals” to be spread around the world, according to new research. Researchers led by Lancaster University estimate that around a third of 1 million tonnes (335,500 tonnes) of trifluoroacetic acid (TFA) was deposited from the atmosphere to the earth’s surface between 2000 and 2022 due to CFC replacement chemicals and certain anesthetics. The findings suggest that the problem is still growing. TFA pollution is expected…