The American Gastroenterological Association (AGA) today announced the launch of Nigel, an artificial intelligence (AI)-powered virtual assistant developed specifically for gastroenterology and hepatology. Built using AGA’s trusted clinical guidance and developed in collaboration with experts Dennis L. Shun, MD, MHS, Bradley C. Steady, MD, and Allie T. Strauss, MD, MIE, Nigel provides clinicians with fast, evidence-based answers designed for the complexities of gastrointestinal disease care.
As gastroenterologists, we need answers we can trust in our practice. Nigel offers just that. With guideline-driven answers in seconds, you can have more confidence in your clinical decisions without wondering where the information came from. ”
Russ Arjal, MD, AGAF, and AGA Board of Directors General Development and Growth Councilor
As a trusted digital colleague, Nigel:
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We provide concise, evidence-based answers based on the latest information in AGA clinical guidelines and clinical practice.
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Interpret and summarize clinical guideline recommendations based on the AGA’s Recommendations Assessment, Development, and Evaluation (GRADE).
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Provide supporting evidence and relevant research to inform clinical decisions.
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Helps clinicians validate diagnostic and treatment decisions.
Unlike common AI tools trained on extensive internet data, Nigel is built on AGA’s peer-reviewed clinical guidelines, structured around the GRADE evidence framework, and vetted by a panel of gastrointestinal and liver experts to ensure clinical accuracy. The platform provides transparent, guideline-based clinical guidance that describes the strength of available evidence and areas of uncertainty.
“When clinical questions arise, clinicians need answers they can trust,” says Allie T. Strauss, Ph.D., assistant professor of medicine at Johns Hopkins University School of Medicine. “Nigel will combine AGA’s evidence-based guidance with the expertise of leading gastroenterology and hepatology experts to provide fast and reliable clinical support at the point of care. Our goal is to help clinicians spend less time looking for information and more time caring for their patients.”
In addition to supporting clinical decision making, Nigel helps reduce the cognitive burden on clinicians by allowing them to:
Nigel’s knowledge base is updated in real-time as the AGA issues new clinical guidance or new evidence changes clinical recommendations, ensuring users always have access to the latest evidence-based guidance.
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American College of Gastroenterology

