In March, it lost the top spot to Johnson & Johnson’s immunotherapy drug Tremfya, but AbbVie’s rival drug Skyrizi has regained the top spot in advertising.
AbbVie spent $46.8 million advertising Skyridi in April, an increase of $4.7 million from the previous month, putting the drug comfortably ahead of Tremfya.
J&J’s drugs came in second with the biggest spending cut of $10.6 million, according to data shared by iSpot.tv analysts with Fierce Pharma Marketing.
AbbVie’s other leading immunologist, Rinvoke, held onto third place in April, but in a close race with J&J, Rinvoke’s ad spend was just $200,000 behind Tremfya.
Eli Lilly increased spending on its obesity drug Zepbound by $1.5 million, pushing the drug up one spot from March to No. 4.
Up two spots to No. 5 is Sanofi and Regeneron’s immunology blockbuster Dupixent, with most of the $20.4 million spent last month on advertising related to its eczema indication.
Johnson & Johnson returned to the list with its atypical antipsychotic drug Caprita, but fell two spots to No. 6 as spending fell from $23.4 million in March to $20.2 million in April.
Lundbeck and Otsuka Pharmaceutical’s depression drug Rexulti came in seventh place, while Eli Lilly and Boehringer Ingelheim’s diabetes and kidney disease drug Jardiance moved from sixth place in March to eighth place due to an $8.2 million drop in spending.
The final two spots went to AbbVie’s atypical antipsychotic Vreilor (which dropped from the rankings in March but returned to ninth place) and Neurocline’s Ingrezza, which is approved to treat tardive dyskinesia and chorea associated with Huntington’s disease.
See April’s biggest ad spenders below, based on data compiled by iSpot.tv’s analysts.
1. Skiriji
Movement: move up one rank
What is it? AbbVie’s immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $46.8 million (up from $42.1 million in March)
- UC/Crohn’s disease: $21.4 million
- Psoriasis: $22.9 million
- Psoriatic arthritis: $2.5 million
Top TV networks by share of voice spend (SOV):ABC (23.18%)
Spending SOV Top TV Shows by: Sports center (2.19%)
Number of spots: 5 patients (1 patient with psoriatic arthritis, 2 patients with psoriasis, 2 patients with UC/Crohn’s disease)
Biggest ticket ad: “I’m All In: Swimming Pool” (estimated at $21.4 million)
2. Tremfia
Movement: went down one
What is it? johnson & johnson immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $39.7 million (down from $50.3 million in March)
- UC/Crohn’s disease: $25.8 million
- Psoriasis: $1.2 million
- Psoriatic arthritis: $12.8 million
Top TV Networks by SOV Spending: ABC (19.76%)
Spending SOV Top TV Shows by: Men’s College Basketball (7.60%)
Number of spots: 8 patients (3 with psoriatic arthritis, 1 with psoriasis, 4 with UC/Crohn’s disease)
Biggest ticket ad: “Relentless Weed” (est. $12.7 million)
3. Revocation
Movement: no movement
What is it? AbbVie’s JAK inhibitor immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $39.5 million (up from $36.3 million in March)
- Arthritis: $10 million
- Eczema: $11.2 million
- UC/Crohn’s disease: $18.3 million
Top TV Networks by SOV Spending: ABC (27.52%)
Spending SOV Top TV Shows by: Today (4.50%)
Number of spots: 7 cases (2 arthritis, 2 ulcerative colitis/Crohn’s disease, 3 eczema)
Biggest ticket ad: “Classic cars, tennis, and the fire department” (estimated at $18.2 million)
4. Zep Bound
Movement: move up one rank
What is it? Eli Lilly’s obesity treatment
EST (Eastern Standard Time). National linear TV advertising costs: $24.4 million (up from $22.9 million in March)
Top TV Networks by SOV Spending:CBS (20.16%)
Spending SOV Top TV Shows by: Men’s college basketball (30.23%)
Number of spots: Seven
Biggest ticket ad: “Watch This: Head-to-Head” (estimated at $13.1 million)
5. Dupixent
Movement: Moved up 2 places
What is it? Sanofi and Regeneron’s immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $20.4 million (up from $19.6 million in March)
- Eczema: $13.7 million
- Asthma: $6.7 million
- Gastrointestinal: $36.5,000
Top TV Networks by SOV Spending: ABC (32.31%)
Spending SOV Top TV Shows by: Men’s college basketball (6.57%)
Number of spots: 8 cases (3 cases of asthma, 4 cases of eczema, 1 case of gastrointestinal disease)
Biggest ticket ad: “Feel the Heel” (est. $8.2 million)
6. Caprita
Movement: Moved down 2 places
What is it? Johnson & Johnson’s atypical antipsychotic
EST (Eastern Standard Time). National linear TV advertising costs: $20.2 million (down from $23.4 million in March)
Top TV Networks by SOV Spending:ABC (19.61%)
Spending SOV Top TV Shows by: 2026 NFL Draft (4.91%)
Number of spots: three
Biggest ticket ad: “Let in the Lyte: More Relief” (estimated at $7.5 million)
7. Rejected
Movement: move up one rank
What is it? Lundbeck-Otsuka nerve drug
EST (Eastern Standard Time). National linear TV advertising costs: $17.8 million (up from $16.5 million in March)
Top TV Networks by SOV Spending:CBS (16.32%)
Spending SOV Top TV Shows by: NCIS (4.32%)
Number of spots: two
Biggest ticket ad: “Progress” (estimated at $17.8 million)
8. Jardiance
Movement: Moved down 2 places
What is it? Eli Lilly and Boehringer Ingelheim’s diabetes and kidney disease treatments
EST (Eastern Standard Time). National linear TV advertising costs: $12.6 million (down from $20.8 million in March)
- CKD: 3 million dollars
- Diabetes: $9.7 million
Top TV Networks by SOV Spending: ABC (20.55%)
Spending SOV Top TV Shows by: ABC World News Tonight, David Muir (4.64%)
Number of spots: 2 people (1 person with CKD, 1 person with diabetes)
Biggest ticket ad: “Behind the Scenes” (estimated at $9.7 million)
9. Vrayz
Movement: Not posted last month
What is it? AbbVie’s atypical antipsychotics
EST (Eastern Standard Time). National linear TV advertising costs: $12.1 million (up from $10.5 million in March)
- Bipolar disorder: $4.5 million
- Depression: $7.6 million
Top TV Networks by SOV Spending: ABC (9.68%)
Spending SOV Top TV Shows by: NBA (6.54%)
Number of spots: 3 people (2 with depression, 1 with bipolar disorder)
Biggest ticket ad: “Jane’s Head” (est. $7.5 million)
10. Dishonesty
Movement: Not posted last month
What is it? Neurosecretory tardive dyskinesia and chorea associated with Huntington’s disease drugs
EST (Eastern Standard Time). National linear TV advertising costs: $11 million (up from $8 million in March)
Top TV Networks by SOV Spending:CBS (19.09%)
Spending SOV Top TV Shows by: ABC World News Tonight, David Muir (7.71%)
Number of spots: two
Biggest ticket ad: “Flowing Stories” (estimated at $11 million)
