Men who naturally prefer to stay up late may be more susceptible to premature ejaculation later in life, and often experience more severe symptoms than men who rise early. Recent research has found that this association is partially related to lifestyle habits, highlighting how sleep preferences and daily activities can affect sexual function. This research Sexual medicine journal.
Premature ejaculation is one of the most common sexual health conditions affecting men around the world. Doctors classify it into two main subtypes based on when symptoms begin. Lifelong premature ejaculation is present from the first sexual encounter. This condition, which can develop later in life after a period of normal sexual function, is known as acquired premature ejaculation.
Men experiencing acquired symptoms often face a sudden onset of symptoms. This condition usually reduces the time to ejaculation to less than 3 minutes. This rapid change can cause considerable psychological distress and rapidly impair a person’s overall quality of life.
Medical experts have identified several risk factors for this acquired sexual dysfunction. Chronic pelvic pain, anxiety, and thyroid issues are all known to play a role. However, the exact biological and behavioral causes of this condition remain somewhat mysterious.
In clinical practice, physicians have noticed a recurring pattern among patients treating acquired premature ejaculation. Many of these men seemed to prefer later bedtimes and experienced irregular sleep schedules. They also suffered from emotional instability and struggled to maintain a healthy daily routine.
This observation led doctors to wonder if a person’s innate biological clock might influence ejaculation control. Chronotype refers to an individual’s natural internal circadian rhythm. This biological preference determines an individual’s ideal sleep and wake times in a 24-hour cycle.
Based on this natural rhythm, people are generally categorized as morning owls, mid-morning owls, and night owls. People with night chronotypes, colloquially called night owls, often experience poor sleep quality. They are also more susceptible to anxiety and depressive symptoms, which are already known risk factors for sexual dysfunction.
Lead author Zhi Cao and a research team from China’s First Affiliated Hospital of Anhui Medical University and Peking University First Hospital designed an observational study to explore this potential link. They wanted to see if evening chronotype correlated with the presence and severity of acquired premature ejaculation.
The researchers also sought to understand whether certain behavioral habits play a role in bridging this gap. Specifically, we focused on a health-promoting lifestyle that includes positive habits such as a nutritious diet, regular exercise, and active stress management. Previous research has linked these positive habits to improved erectile function and lower risk of overall sexual dysfunction.
Because night owls often exercise less and sleep more irregularly than morning owls, the researchers developed a testable hypothesis. They speculated that lifestyle habits might mediate the relationship between chronotype and ejaculatory control.
1,011 adult men participated in this study. The sample included 516 patients previously diagnosed with acquired premature ejaculation and 495 healthy control subjects. Control participants were matched to the patient group based on age, BMI, and history of drug use to ensure equal comparison.
Participants completed a series of paper questionnaires during their clinic visit. These studies assessed ejaculatory control, baseline erectile function, and natural position on the morning-to-evening chronotype spectrum. The survey also assessed men’s regular engagement in lifestyle habits that promote health.
Men in the diagnosed group completed an additional questionnaire to measure their awareness of the disease. This concept refers to how threatening, persistent, and uncontrollable the patient believes his or her condition to be. High illness awareness means that patients feel a great deal of burden or despair about their symptoms, while low illness awareness means that patients believe their condition is manageable.
Researchers found that men with acquired premature ejaculation had lower global morningness and lifestyle scores than healthy control subjects. Statistically, having an evening chronotype was associated with the presence of the condition. Among men dealing with this dysfunction, there was a correlation between being more likely to stay up late and having worse ejaculatory control.
Disrupted circadian rhythms, which are common in night owls, may explain this association at a biological level. These internal cycles regulate numerous physiological processes, including the production of important neurotransmitters such as serotonin and dopamine. Animal studies have shown that serotonin levels fluctuate in a circadian pattern and that serotonin in the central nervous system is closely related to ejaculatory latency.
Disruption of these monoamine systems can impair the body’s ability to delay ejaculation. Statistical analysis of the current study reveals that a secondary behavioral pathway is at work. The association between sleep preferences and sexual function in the patient group was partially explained by daily habits.
Evening people tended to engage in fewer health-promoting behaviors. Declines in these health habits were correlated with worsening symptoms. The data showed that lifestyle accounted for a significant portion of the association between chronotype and symptom severity.
Patients’ individual perceptions of their condition altered these relationships. For men who feel a strong sense of threat and lack of control over their sexual health, the positive association between being a morning person and having better lifestyle habits is attenuated. A similar attenuation was seen in the association between healthy habits and symptom severity.
When men feel overwhelmed by their condition, the potential benefits of regular exercise, nutrition, and stress management appear to be diminished. High anxiety and constant vigilance for symptoms consume cognitive and emotional resources. This heavy psychological burden can reduce the energy available to maintain a healthy daily life.
Because the study relied on taking a snapshot of data at a single point in time, the researchers can’t say that staying up late can directly cause acquired premature ejaculation. The observed relationships may operate in multiple directions. Repeated failures in ejaculatory control often lead to severe sexual performance anxiety.
This anxiety activates the sympathetic nervous system and can make it difficult to initiate sleep. Gradually delaying your bedtime can strengthen your nocturnal chronotype over time. To reliably validate this cycle, patients must be observed over multiple years.
Participants were selected from one hospital in China, so the demographic sample was limited. Testing these variables in different cultural contexts and broader community settings can help validate patterns. Researchers also rely on self-report questionnaires, which are susceptible to recall bias and social desirability bias.
Researchers did not formally assess clinical anxiety or depressive symptoms beyond basic screening. Because these mental health factors significantly impact sleep, lifestyle, and sexual function, future research will need to incorporate standardized psychological assessments to better understand the dynamics at play.
Future studies will need to follow men over longer periods of time to see how sleep preferences and health habits evolve along with sexual function. Ultimately, clinical trials could test whether targeted actions, such as improving eating habits or adjusting sleep schedules, actually improve ejaculatory control. In the meantime, health care professionals may benefit from asking about patients’ sleep timing, daily lifestyle, and emotional responses to symptoms during routine visits.
The study, “Chronotype is associated with acquired premature ejaculation: Evidence from moderated mediation analysis,” was authored by Zhi Cao, Tianle Zhu, Yunlong Ge, Peng Yang, Yukuai Ma, Pan Gao, Hui Jiang, and Xiansheng Zhang.

