Researchers from Radboud University, Oxford University, and Cambridge University set out to test a surprising idea. Can we simply change people? expect How can I change my preference for sweet drinks? Their findings were; JNeuroscisuggests the answer is “yes”.
The research team surveyed 99 healthy adults with an average age of 24. The participants were chosen because they had similar opinions about sugar and artificial sweeteners. Most people reported that they liked both about equally.
But when researchers subtly changed what participants believed they were drinking, their experiences changed. When people are told that they are drinking a drink containing artificial sweeteners, they rate sugary drinks as less enjoyable. On the other hand, when participants thought the drink contained sugar, they reported enjoying it more, even if it actually contained artificial sweeteners.
Brain imaging studies reveal that these expectations don’t just influence opinions; They also affected activity in key reward-related areas of the brain. This region became more active when participants believed they were drinking sugar, even when there was actually no sugar in the drink.
Dr. Westwater said, “This may mean that this brain region, the dopaminergic midbrain, processes the increased nutrients and calories of sweet flavors, supporting rodent studies showing that this brain region is important for sugar seeking.”
The results highlight how expectation plays a powerful role in both sweetness-related behavior and brain activity. In other words, what people think they’re consuming can shape not only their taste perception, but also how their brains respond to taste.
Westwater also pointed to potential real-world applications, particularly in improving eating habits. “Emphasizing that healthier food alternatives are ‘nutritious’ or ‘contains minimal added sugar’ may create more positive expectations than using terms like ‘diet’ or ‘low calorie’. This may help people align their food choices with their brain’s calorie preferences, while supporting behavior change.”
Although these ideas are not entirely new in clinical practice, the researchers believe this study adds valuable insights. Westwater hopes the findings will influence how scientists approach research into eating behavior and nutrition in the future.

