Johnson & Johnson’s immunotherapy drug Tremfya is poised to challenge AbbVie’s dominance in 2026 and secure the top spot as the biggest TV drug ad spender in March.
J&J spent $50.3 million on TV advertising for its drugs, according to data shared with Fierce Pharma Marketing by analysts at iSpot.tv. That’s an increase of more than $10 million from February, which was second in spending.
Tremfya started the year in the top spot in January and is on track to match AbbVie’s dominance early on. AbbVie has won the annual crown for one of its blockbuster drugs as the top TV spender in each of the past four years.
But AbbVie is still in the fight, with immunology duo Skyrizi and Rinvoq taking the podium spot behind J&J with $42.1 million and $36.3 million, respectively. Rinvok fell two places after taking the lead in February.
J&J is back in fourth place with its atypical antipsychotic Caprita, which moved up two spots from February’s ranking and saw spending increase by $5.5 million from the previous month.
Eli Lilly’s obesity drug Zepbound moved up two spots to No. 5, with the company’s highest-grossing television ad, “Watch This: Head-to-Head,” accounting for $12.3 million in March.
Lilly returned to sixth place with its diabetes and kidney disease drug Jardiance, tied with partner Boehringer Ingelheim, while Sanofi and Regeneron’s blockbuster immunotherapy drug Dupixent came in seventh.
Lundbeck and Otsuka’s Nerve Agent missed out on the top 10 in February, but returned to No. 8 in March.
Spending fell six places to ninth place, from $39.5 million in February to $13.5 million last month, due to a big drop in Novo Nordisk’s obesity drug Wegovy.
Bristol-Myers Squibb’s schizophrenia drug did not rank in the top 10 in February, but has slipped into the final rankings.
Check out the top 10 below compiled by iSpot.tv’s analysts.
1. Tremfia
Movement: move up one rank
What is it? johnson & johnson immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $50.3 million (up from $39.8 million in February)
- UC/Crohn’s disease: $33 million
- Psoriasis: $5 million
- Psoriatic arthritis: $12.3 million
Top TV networks by share of voice spend (SOV):ABC (17.69%)
Spending SOV Top TV Shows by: Men’s college basketball (5.34%)
Number of spots: 11 patients (3 with psoriasis, 5 with UC/Crohn’s disease, 3 with psoriatic arthritis)
Biggest ticket ad: “Relentless Weed” (est. $15.3 million)
2. Skiriji
Movement: Moved up 2 places
What is it? AbbVie’s immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $42.1 million (up from $37 million in February)
- UC/Crohn’s disease: $21.9 million
- Psoriasis: $15.8 million
- Psoriatic arthritis: $4.3 million
Top TV Networks by SOV Spending: ABC (29.96%)
Spending SOV Top TV Shows by: Oscar Award (12.16%)
Number of spots: 7 patients (2 with psoriatic arthritis, 3 with psoriasis, 2 with UC/Crohn’s disease)
Biggest ticket ad: “In the Picture: Control Is Everything” (est. $11.8 million)
3. Revocation
Movement: Moved down 2 places
What is it? AbbVie’s JAK immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $36.3 million (down from $41 million in February)
Top TV Networks by SOV Spending: ABC (22.42%)
Spending SOV Top TV Shows by: Today (5.46%)
Number of spots: 5 cases (1 case of arthritis, 1 case of ulcerative colitis/Crohn’s disease, 3 cases of eczema)
Biggest ticket ad: “Another Day” (est. $13 million)
4. Caprita
Movement: Moved up 2 places
What is it? Johnson & Johnson’s atypical antipsychotic
EST (Eastern Standard Time). National linear TV advertising costs: $23.4 million (up from $17.9 million in February)
- MDD: $23.2 million
- Bipolar disorder: $154,000
Top TV Networks by SOV Spending:NBC (15.15%)
Spending SOV Top TV Shows by: Men’s college basketball (20.33%)
Number of spots: 5 (2 bipolar disorder, 3 MDD)
Biggest ticket ad: “Let in the Lyte: More of the Lyte” (estimated at $9.4 million)
5. Zep Bound
Movement: Moved up 2 places
What is it? Eli Lilly’s GIP/GLP-1 agonist for obesity
EST (Eastern Standard Time). National linear TV advertising costs: $22.9 million (up from $17.2 million in February)
Top TV Networks by SOV Spending: ABC (32.12%)
Spending SOV Top TV Shows by: Men’s college basketball (43.14%)
Number of spots: Seven
Biggest ticket ad: “Watch This: Head-to-Head” (estimated at $12.3 million)
6. Jardiance
Movement: Moved up 3 places
What is it? Eli Lilly and Boehringer Ingelheim’s diabetes and kidney disease treatments
EST (Eastern Standard Time). National linear TV advertising costs: $20.8 million (up from $15 million in February)
- CKD: $13.4 million
- Diabetes: $7.4 million
Top TV Networks by SOV Spending: ABC (24.79%)
Spending SOV Top TV Shows by: ABC World News Tonight, David Muir (6.06%)
Number of spots: 3 people (1 person with CKD, 2 people with diabetes)
Biggest ticket ad: “Not So Fast: Garden” (estimated at $13.4 million)
7. Dupixent
Movement: move up one rank
What is it? Sanofi and Regeneron’s immunotherapy
EST (Eastern Standard Time). National linear TV advertising costs: $19.6 million (up from $15.5 million in February)
- Eczema: $15 million
- Asthma: $4.6 million
- Gastrointestinal: $16,800
Top TV Networks by SOV Spending: ABC (30.44%)
Spending SOV Top TV Shows by: Men’s College Basketball (39.70%)
Number of spots: 8 cases (3 cases of asthma, 4 cases of eczema, 1 case of gastrointestinal disease)
Biggest ticket ad: “Feel the Heel” (est. $9.6 million)
8. Rexulti (depression)
Movement: Not posted last month
What is it? Lundbeck-Otsuka nerve drug
EST (Eastern Standard Time). National linear TV advertising costs: $16.5 million (up from $13 million in February)
Top TV Networks by SOV Spending: CBS (12.99%)
Spending SOV Top TV Shows by: NCIS (4.34%)
Number of spots: two Biggest ticket ad: “Park & Arcade” (estimated at $14.9 million)
9. Wegs
Movement: Moved down 6 places
What is it? Novo Nordisk’s obesity treatment
EST (Eastern Standard Time). National linear TV advertising costs: $13.5 million (down from $39.5 million in February)
Top TV Networks by SOV Spending: ABC (38.16%)
Spending SOV Top TV Shows by: Men’s college basketball (56.05%)
Number of spots: two
Biggest ticket ad: “A New Path” (estimated at $7.6 million)
10. Kobenfi
Movement: Not posted last month
What is it? Bristol-Myers Squibb’s schizophrenia drug
EST (Eastern Standard Time). National linear TV advertising costs: $11.4 million (down from $12.6 million in February)
Top TV Networks by SOV Spending:CBS (25.77%)
Spending SOV Top TV Shows by: Men’s college basketball (27.69%)
Number of spots: two
Biggest ticket ad: “The Sagan Story” (est. $11.4 million)
