Author: healthadmin

Scientists at Stellenbosch University (SU) have discovered the first evidence of a group of rare phenolic compounds known as flaboalkaloids. cannabis Leaves add an amazing new dimension to a plant’s chemical reactions. Phenolic compounds, especially flavonoids, are already highly valued in medicine for their antioxidant, anti-inflammatory, and anticarcinogenic properties. This new discovery suggests that cannabis It may contain many more biologically important compounds than previously realized. Dozens of previously unknown cannabis compounds identified In their study, researchers analyzed three types of commercially grown plants. cannabis We extracted a strain from South Africa and identified 79 phenolic compounds. Of these, 25…

It is widely known that chronic stress disrupts the balance of digestion and causes symptoms such as diarrhea and constipation. New research results, scheduled to be presented at Digestive Disease Week (DDW) 2026, suggest that eating late at night can exacerbate these problems, with potential effects on both digestive function and the gut microbiome. “It’s not just what you eat, it’s when you eat,” says Harika Dadigiri, M.D., a resident at New York Medical College’s St. Mary’s and St. Clare Hospital and lead author of the study. “And when we’re already under stress, that timing can deliver a ‘double whammy’…

1. Liberation lifts the spiritThe most important takeaway from the first Fossil Fuel Transition Conference in Santa Marta was a change of mood. Almost all participants in Colombia felt liberated at the annual United Nations Climate Summit (COPS), which can often feel bogged down and frustrating as countries debate the same topic without solutions.“The atmosphere here in Santa Marta is euphoric,” said Tzeppola Berman, founder and chair of the Treaty on the Non-Proliferation of Fossil Fuels Initiative. “After years of being mired in endless debates about whether or not fossil fuels should be phased out, we are finally focusing on…

New research reveals how lipids released after meals can sustainably boost the metabolic, translational and immune capabilities of T cells, with implications for infectious disease research and next-generation cell therapies. Research: Postprandial lipid metabolism permanently enhances T-cell immunity. Image credit: Vink Fan / Shutterstock In a recent study published in the journal natureA group of researchers investigated how short-term postprandial nutritional status affects T cell metabolism, activation, and long-term immune function. Postprandial nutrition and T cell function Can the timing of your last meal affect your body’s effective response to infection? The immune system relies on energy and can be…

Researchers from the University of Melbourne have explained for the first time how Australia’s famous Twelve Apostles were created. Their findings show that millions of years of tectonic plate movement gradually lifted these giant rock formations and tilted them away from the ocean. Until now, scientists had only a limited understanding of how the Twelve Apostles developed into the landmarks we see today. Natural record of ancient climate and sea level Research lead researcher Associate Professor Stephen Gallagher, from the University of Melbourne’s School of Geography, Earth and Atmospheric Sciences, said this tectonic activity gave the Apostles one of the…

A targeted GLP-1-GIP-lanifibranol complex conferred broad metabolic benefits in obese mice, suggesting the potential of a new generation of multipathway therapies against obesity and type 2 diabetes. Study: GLP-1R-GIPR-PPARα/γ/δ 5 heavy agonism improves obesity and diabetes in mice. Image credit: zimmytws / Shutterstock Recent research published in journals nature We describe the creation of a novel single-molecule penta-agonist designed to integrate ranifibranol’s anti-inflammatory effects and insulin-sensitivity properties with incretin-mediated metabolic regulation. In preclinical models, this compound showed superior efficacy to semaglutide and glucagon-like peptide-1 receptor (GLP-1R)-glucose-dependent insulinotropic polypeptide receptor (GIPR) combination therapy, significantly reducing body weight, food intake, and blood…

Fat cells, also known as adipocytes, are more than just passive storage units that store excess body weight. These play an active role in managing how the body uses and stores energy. Inside these cells, fat is packed into structures called lipid droplets, which act as fuel stores that the body can use when needed, such as when fasting between meals. To release this stored energy, the body relies on a protein called HSL. This protein acts like a switch. When energy levels drop, hormones such as adrenaline activate HSL, causing the release of fat that can be utilized by…

A multicondition polygenic risk report validated in the U.S. health care system could help clinicians detect inherited cardiovascular risks earlier, refine prevention strategies, and guide more individualized care. Research: Development and validation of a clinical polygenic risk report for eight cardiovascular diseases in a US-based health system. Image credit: ArtemisDiana / Shutterstock In a recent study published in Journal of the American College of Cardiology (JACC)researchers described the development and validation of a unified polygenic risk score (PRS) for eight cardiovascular diseases using data from 245,394 All of Us (AOU) Research Program participants and 53,306 Mass General Brigham Biobank (MGBB)…

NEWARK, N.J. — OxyContin maker Purdue Pharma will be dissolved and replaced by a company focused on the public interest by the end of this week, as a major legal settlement that resolves thousands of lawsuits goes into effect. A federal judge sentenced the company Tuesday to a criminal sentence to resolve the Justice Department investigation, the final step needed to pave the way for a settlement. STAT Plus: ‘The scum of the earth’: Opioid crisis victims confront Purdue Pharmaceutical executives U.S. District Judge Madeline Cox Arleo made the decision after hearing hours of shocking statements from people who had…

New benchmarks show that passing a medical exam is not enough. Clinical AI agents must gather information, deal with uncertainty, use tools, interpret images, and avoid bias in simulated patient encounters. Run the language agent in AgentClinic. (Left) Agent workflow diagram for AgentClinic. The physician agent interacts with tools and agents to arrive at a diagnosis. The moderator agent compares the conclusion with the true diagnosis at the end of the simulation. (Right) Example of interaction between agents in the AgentClinic benchmark. Recent research published in journals npj digital medicine introduced AgentClinic, a multimodal agent benchmark for clinical artificial intelligence…