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Author: healthadmin
High doses of curcumin fail to produce lasting changes in the gut microbiota of IBD patients
Even at pharmacological doses that flood the colon but barely enter the bloodstream, curcumin’s effects on the gut microbiome were found to be temporary, highlighting the remarkable resilience of the human microbial ecosystem. Study: Effects of curcumin on the intestinal microbiota of ulcerative colitis, Crohn’s disease patients and healthy participants. Image credit: Faizal Ramli / Shutterstock In a recent study published in the journal scientific reportResearchers assessed health-related quality of life (HRQoL) and 4-year mortality in patients with COVID-19-associated acute respiratory distress syndrome (ARDS) treated in intensive care units (ICUs). Background and rationale A large cohort of COVID-19 survivors with…
COVID-19 ARDS survivors face permanent disability and high late mortality rates, researchers report
Four years after admission to the ICU, the mortality rate for mechanically ventilated ARDS patients with COVID-19 remains extremely high, and many survivors continue to struggle with fatigue, insomnia, functional decline, and decreased quality of life. Study: Four-year mortality and quality of life after ICU treatment for COVID 19-related acute respiratory distress syndrome. Image credit: Design_Cells / Shutterstock In a recent study published in the journal scientific reportResearchers assessed health-related quality of life (HRQoL) and 4-year mortality in patients with COVID-19-associated acute respiratory distress syndrome (ARDS) treated in intensive care units (ICUs). Background and rationale A large cohort of COVID-19…
The Department of Health and Human Services (HHS) has told employees they can no longer use Claude, Anthropic’s generative artificial intelligence tool, as President Donald Trump seeks to place the company on a federal blacklist. Although Claude is currently off-limits, similar tools such as OpenAI’s ChatGPT Enterprise and Google Gemini “remain available for authorized mission-related use,” HHS spokeswoman Emily Hilliard confirmed to Fierce Biotech. Claude’s loss could hamper the FDA’s efforts to speed up the drug review process, which was repeatedly delayed during President Trump’s second term. Last summer, regulators rushed to launch an AI tool called Elsa a month…
A recent Office of Inspector General (OIG) investigation revealed the alarming statistic that approximately half of all patient harm incidents are missed in U.S. hospitals. While this number definitely indicates a failure, it is not an intended failure or a failure of individual providers. The bottom line is that our systems as built today do not provide a complete picture of the safety risks facing patients. At the heart of this report is a simple fact: If we can’t see harm happening, we can’t prevent it. Although healthcare has made significant advances in recent years in reducing infections, preventing falls,…
Pharmaceutical companies focus on safety and access to medicines as Middle East war breaks out
As the effects of the weekend’s U.S. and Israeli attacks on Iran begin to reverberate across the Middle East, several pharmaceutical companies operating in the region are taking early steps to ensure the safety of local employees and ensure continued access to medicines in neighboring countries affected by the ongoing conflict. The United States and Israel launched attacks across Iran on February 28, following a large-scale military buildup by the United States in the Middle East in recent weeks. In response, Iran launched retaliatory attacks not only on Israel but also on neighboring countries that host U.S. military bases, such…
Study finds that entitled and exploitative people are more likely to treat others as objects
A study conducted in Poland found that people who are agreeable, intellectually curious, and uphold positive norms of reciprocity are less likely to objectify others. In contrast, people who tended to exploit others or who had a strong sense of entitlement were more likely to objectify others. This study Current issues in personality psychology. Objectification of people is the act of treating people primarily as objects rather than as fully human beings with thinking, feeling, and autonomy. This involves ignoring individuality and reducing someone to their body, appearance, usefulness, or a single characteristic (or set of characteristics). Objectification is most…
The elimination of the Common Use Act for Motorcycle Helmets is associated with significant increases in crash-related hospitalization costs, according to research published in . Journal of the American College of Surgeons (jacks). Using Michigan’s 2012 repeal as a natural experiment, researchers found that the policy change increased average hospital costs per motorcycle accident patient by 26%. When people argue that helmet choice is simply a matter of personal freedom, they overlook who ultimately pays for the treatment. A significant portion of these costs falls on public payers, taxpayers, and the trauma system, which means we all share the…
Companies challenging the EPA’s rules for phasing out powerful heat-trapping chemicals are asking the Supreme Court to reinstate a doctrine that limits the power Congress can delegate to federal regulators. The New Civil Liberties Union, which represents companies involved in the refrigerant aftermarket, asked the high court to overturn a 2025 District of Columbia Circuit Court of Appeals decision that upheld the EPA’s method of allocating hydrofluorocarbon production and consumption. The EPA’s HFC phaseout is mandated by the American Innovation and Manufacturing Act, a 2020 law signed by President Donald Trump during his first term. This law gave the EPA…
Ten years ago, discussions in Milan set a difficult project in motion. At the meeting with biologists and urologists, questions kept coming up. Why do so many bladder cancer patients face recurrence even after undergoing surgery that follows all guidelines? This initiative focuses on successful projects funded by the European Innovation Council (EIC). Featured on DeepSync, part of the EIC Community Project, these stories offer a unique opportunity to connect with fellow members and innovators. By showcasing the challenges and successes along each project’s journey, these stories highlight key moments and insights, increasing visibility, fostering deeper understanding, and fostering collective…
Your brain begins as a single cell. After all, it houses an incredibly complex and powerful network of about 170 billion cells. How does it organize itself along the way? Neuroscientists at Cold Spring Harbor Laboratory have discovered a surprisingly simple answer that could have far-reaching implications for biology and artificial intelligence. Stan Kerstiens, a postdoctoral fellow in Professor Anthony Zador’s lab, frames this question in terms of location. “A cell ‘sees’ only itself and its neighbors,” he explains. “But the fate of a cell is determined by where it is located. If a cell is in the wrong place,…