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In addition to the newly approved lung disease drug Brin Supplement, which InsMed expects to be a blockbuster this year, the New Jersey company revealed trial results for its older lung disease drug Aricais, which could pave the way for a major label expansion. The Phase 3b Encore study tested the antibiotic combination of inhaled Aricace and azithromycin and ethambutol versus the antibiotic combination plus a placebo in patients with newly diagnosed Mycobacterium avium complex (MAC) lung infections. The study met primary and multiplicity-controlled secondary culture conversion endpoints, the company said in a March 23 release. The Arikayce regimen demonstrated…
Researchers found significant flaws in historic clinical trials used to justify spanking
Recent research suggests that there is no experimental evidence to prove that corporal punishment is an effective method of disciplining children. The results of this study show that alternative, non-physical strategies can be just as effective at encouraging children’s cooperation, without the potential risks associated with spanking. The study was published in the journal Child Abuse and Neglect. Spanking remains a widespread form of discipline and is considered normative and socially acceptable in many cultures. Despite disapproval from some health organizations, it is estimated that two out of three children between the ages of two and four are spanked worldwide.…
‘Back to normal’: Washington DC’s sewage response moves to cleanup | Pollution and solutions
U.S. Army Corps of Engineers contractors are removing leaves and soil contaminated by untreated sewage spilled into the Potomac River in January 2026. dave harp In a wooded ravine dozens of yards from the north bank of the Potomac River, workers wear white protective suits, thick gloves, rubber boots, hard hats and respirators. They spent hours using garden hoes and rakes to scrape out the top few inches of soil and whatever was in it.In this case, “anything” means everything from human waste and toilet paper flushed down the toilet, to dirty dishwater, food scraps, and grease that spilled out…
Novartis is the latest multinational drug manufacturer to prepare to ramp up its research and production operations in China as pharmaceutical investment capital flows out of the country. The Swiss pharmaceutical company plans to invest a total of more than 3.3 billion Chinese yuan (approximately $480 million) to expand its manufacturing facilities in Beijing and strengthen its research and development campus in Shanghai, where the company’s Chinese headquarters are also located, according to a March 22 post (in Chinese) on the company’s official WeChat account. About 1.5 billion yuan will be spent on the factory renovation, with Novartis telegraphing plans…
Watch out, Johnson & Johnson. Dizar has reported positive Phase 3 results for oral Zegflovy, which could put further pressure on the pharmaceutical giant’s injectable Librevant for non-small cell lung cancer (NSCLC). The global phase 3 Wu-Kong28 trial testing Zegflovi (sambozertinib) as monotherapy met its primary endpoint, Dizal announced on Saturday. EGFR tyrosine kinase inhibitors significantly improved progression-free survival (PFS) compared with platinum-based chemotherapy in previously untreated NSCLC patients with EGFR exon 20 insertion mutations. In addition to a “statistically significant and clinically meaningful” improvement in PFS, Professor Dizal also reported “excellent results” for Zegfrovy in all secondary endpoints measuring…
Everyone alive today has grown up in a world of increasingly extreme weather conditions. Last year, the worst floods in 50 years hit Texas, glaciers in Iceland melted at record speed, a hurricane hit Jamaica with near-unprecedented force, and the world experienced record heat. Scientists warn that the window for change in direction is rapidly shrinking. A report released by the World Meteorological Organization (WMO) on Monday confirms that the Earth’s climate is more out of balance than at any point in recorded history, with effects that will last for centuries and even millennia.Image of Iceland’s melting glaciers experiencing an…
Older people are thought to be able to deal with interpersonal conflict much better than younger people, but new research suggests this advantage may not extend to the modern dating scene. Recent research published in Personality and Social Psychology Bulletin Researchers found that older people in new relationships actually reported worse emotional and physical reactions to their partner’s daily tensions than younger daters. These findings challenge common assumptions about aging and emotional maturity by highlighting how the specific circumstances of fresh relationships can undermine the normal benefits of growing older. Aging often brings with it obvious changes in social and…
Since its introduction nine months ago, the FDA’s National Priority Voucher Testing Program has drawn intrigue and fierce criticism, while also leading to faster approvals for some drugs. With all of this buzz surrounding the program, the agency is now planning to solicit public feedback and consider potential adjustments. The FDA has scheduled a June 12 hearing to hear comments on the Secretary’s National Priority Voucher (CNPV) program, which was introduced last June. In parallel to the in-person event at FDA headquarters in White Oak, Maryland, commenters will have the opportunity to voice their CNPV feedback virtually both before and…
A new study provides new insights into how people judge the environmental impact of the food they eat, and the results suggest that many people get it wrong. These misconceptions clearly demonstrate the need for simple environmental impact labels to guide better choices. Researchers from the University of Nottingham’s School of Psychology asked 168 participants in the UK to categorize different supermarket foods into their own environmental impact categories. The findings revealed consistent misconceptions about which foods are more or less harmful to the environment. This study cleaner production journal. Why food choices matter for the environment Food production plays…
Get the latest news in health technology, digital health and health AI with this weekly overview. News for the week from March 16th to 20th. Perplexity team collaborates with b.well on AI-powered medical records searchArtificial intelligence search engine Perplexity has partnered with b.well Connected Health to integrate consumer health data into its AI-powered search and answer engine. The partnership will allow users to authorize Perplexity to access their health information through b.well’s National Health Data Network, enabling AI responses based on a person’s actual medical history, rather than general information, the companies said. B.well operates a large healthcare data network,…