Author: healthadmin

The chance for Rhythm Pharmaceuticals’ Imshivly to break out of the genetic obesity realm is rapidly approaching with the upcoming FDA decision, but several other areas of potential expansion for this treatment are currently closed off due to failed Phase 3 trials. Rhythm was evaluating the melanocortin 4 receptor (MC4R) agonist Imsivly (cetomelanotide) in four independent substudies targeting obesity due to various genetic factors in the melanocortin 4 receptor (MC4R) pathway. In the trial, called Emanate, patients with heterozygous variants in the POMC/PCSK1, LEPR, SRC1, or SH2B1 genes were randomly assigned to receive a placebo or treatment for 51 weeks.…

Maven Clinic has introduced Maven Intelligence, an artificial intelligence-powered infrastructure built across its virtual clinic, care programs, and benefits platform. The company calls Maven Intelligence an orchestration layer that integrates agent AI with longitudinal data and clinical expertise to personalize care. This layer is built on Maven Clinic’s more than 1 billion structured data points and will begin rolling out to members in March. “Women’s health has been a huge gap in healthcare (for a long time),” Jaya Savkar, Maven’s senior vice president of products, told Fierce Healthcare. “We truly believe we have an opportunity to help close this gap…We…

Moderna CEO Stéphane Bancel’s total compensation last year was surprisingly stable at $19.9 million, even as the vaccine company navigated a “difficult regulatory and business environment.” Moderna’s total revenue fell 40% in 2025, lower than the company’s expectations, while Bancel’s overall salary was about flat, up 0.2% from a year earlier, according to a proxy filing (PDF) issued Monday. Mr. Bancel’s pay package was enhanced by a $4.3 million cash bonus, an increase of nearly 120% from 2024 levels and the highest in its category since Moderna became a public company in 2018. His second-largest non-equity incentive was $2.7 million…

About three weeks have passed since the war between the United States and Israel against Iran began, and the impact of the escalating conflict on regional energy prices and shipping cannot be ignored. As far as trade is concerned, while much of the immediate concern centers on the flow of oil through the Strait of Hormuz, the resulting rise in transportation and energy costs could have ripple effects across industries, including the pharmaceutical industry. And with the war engulfing Iran’s neighbors, multiple experts and media outlets have warned in recent days that if the conflict drags on, local shipments of…

Despite the growing popularity of medical cannabis for mental health and addiction, a new comprehensive review shows little evidence that these products actually help treat most of these conditions. A comprehensive analysis revealed that while cannabis-based medicines may provide mild relief for some specific problems, they do not improve symptoms such as depression and anxiety and carry a higher risk of side effects. These findings were recently published in the journal lancet psychiatry. Cannabinoids are active compounds found in the cannabis plant. The best known of these are tetrahydrocannabinol, which causes the high associated with marijuana, and cannabidiol, a non-intoxicating…

Scientists spent the first few weeks of this year on an expedition to Antarctica to study the Thwaites Glacier, which is melting at an alarming rate. If it completely collapses, it could cause global sea levels to rise by two feet over the next few decades, affecting tens of millions of people around the world, according to a New York Times analysis.The map below shows some of the coastal cities and densely populated low-lying areas that could be under threat if the glacier were to collapse today. kolkata, india 1.7 million Note: Areas below high tide may be protected by…

Lecanemab, sold as Leqembi, is a monoclonal antibody treatment for Alzheimer’s disease that targets and eliminates harmful amyloid plaques while slowing cognitive decline. Scientists from VIB and the University of Leuven have figured out exactly how it works. Their research shows that specific parts of antibodies, known as “Fc fragments,” are important in activating the brain’s immune cells, microglia, which then begin to clear these toxic deposits. This study provides the first clear explanation of how this type of therapy works, answers long-standing questions, and provides guidance for developing safer and more effective treatments for Alzheimer’s disease. The results of…

Generative artificial intelligence programs can be written fluently, but basic scientific descriptions remain difficult to accurately and consistently evaluate. Recent research shows that if you ask artificial intelligence the exact same question multiple times, it often returns completely different answers. These results are rutgers business reviewhighlighting the limitations of current automated reasoning and the continued need for human oversight. Generative artificial intelligence is a type of technology that is trained on large text databases to generate human-like sentences. Today, millions of people use these applications every day for everything from marketing to software development. The software writes in an authoritative…

Listeria monocytogenes is the third leading cause of death from a bacterial foodborne pathogen in the United States, and pregnant people bear a disproportionate share of the burden. However, the scientific models used to develop food safety policy are rarely designed specifically with pregnant people in mind. A new study published in the journal Risk Analysis aims to change that. Each year, approximately 1,250 Americans contract listeriosis, the disease caused by Listeria monocytogenes. The hospitalization rate for this disease is a staggering 86%, and approximately 14% of cases are fatal. For pregnant people, the risk is even higher. Pregnancy-related cases…

Finding effective treatments for osteosarcoma, the most common osteosarcoma in children and young adults, has puzzled medical researchers for 40 years. Now, a new study by researchers at Case Western Reserve University and University Hospitals shows some promising results. This research BMC Medicine, Researchers have discovered that a specially designed immune cell therapy called OSM CAR-T successfully attacks osteosarcoma tumors in a mouse model. According to the Osteosarcoma Institute, osteosarcoma occurs primarily in children, teens, and young adults during periods of rapid bone growth, and approximately 1,000 new cases are diagnosed each year nationwide. The cause is unknown, but is…