Author: healthadmin

Osteoporosis, a common skeletal disease, is characterized by decreased bone mass and deterioration of bone microstructure, making bones more porous and more susceptible to fracture. Bone health is maintained through a continuous remodeling process driven by two specialized cell types: osteoblasts, which build bone, and osteoclasts, which destroy bone. Disruption of this balance plays a central role in the progression of the disease. Current treatments broadly focus on slowing bone resorption by osteoclasts or promoting bone formation by osteoblasts. One widely used approach is anti-sclerostin therapy. It promotes bone formation by reactivating bone lining cells (BLCs), a population of dormant…

Regions with high socio-economic inequality are more susceptible to the effects of cold weather, while regions with high levels of wealth and urbanization are at greater risk during heat waves and lower risk during cold waves. This is shown by a study led by the Barcelona Institute for Global Health (ISGlobal), a center supported by the La Caixa Foundation. The result is natural healthfor the first time quantified how socio-economic inequalities influence temperature-related mortality across urban and rural populations in 32 European countries. The health impacts of climate change are already measurable and will increase in the coming decades unless…

Mental health clinicians are more than five times more likely to think that an evolutionary explanation of anxiety is beneficial to patients than the genetic approach currently taught to trainees and psychiatrists in the UK and US, a new study has shown. The University of Cambridge-led study also found that clinicians in the UK and Ireland were three times more likely to rate a human evolutionary perspective on anxiety as useful for their practice and understanding compared to genetic explanations. The researchers argue that explaining how anxiety has helped our species survive and thrive (essentially, a naturally evolved defense response…

As the FDA decision date for Duchenne muscular dystrophy (DMD) treatment drug Delamiocell approaches, Capricore Therapeutics has filed a lawsuit against its U.S. commercial partner NS Pharma and its parent company Nippon Shinyaku. In a breach of contract lawsuit filed in New Jersey Superior Court, Capricor alleges that NS Pharma failed to “adequately prepare” for the commercial launch of Delamiocell. The San Diego rare disease expert added in the complaint that NS Pharma “dropped the pencil” and halted preparations for launch after the FDA first rejected Delamiocell in a complete response letter (CRL) last July. Capricor is seeking an injunction…

Recent research suggests that temporary states of sexual arousal may cause men to treat women as sexual objects, shifting their focus from psychological characteristics to sexualized physical characteristics. This change occurs independently of a person’s general personality traits, providing evidence that momentary biological states play a central role in how people perceive others. This study Journal of Sex Research. The authors of the new study sought to better understand the immediate and short-term causes of sexual objectification. Sexual objectification occurs when a person is reduced to their sexual function and their mental and emotional characteristics are ignored. In heterosexual situations,…

When Gilead Sciences released its first sales forecast for its twice-yearly pre-exposure prophylaxis (PrEP) treatment Eztugo (lenakapivir) earlier this year, analysts called the company’s $800 million outlook “likely” conservative and “very doable.” Now that Eztugo’s launch trends have become more clear over the past few months, the company has edited its forecasts to favor the billion-dollar opportunity the drug has in 2026. Through the first quarter, the long-acting injectable drug generated sales of $166 million. This is an “unprecedented launch trajectory” and has so far “exceeded our expectations,” explained Chief Commercial Officer Johanna Mercier on the company’s first quarter earnings…

The Supreme Court is expected to take further action in the case by the end of Monday, after ordering a one-week stay on a federal appeals court’s decision blocking the mail-order sale of the abortion drug mifepristone. How the court proceeds could have major implications for Food and Drug Administration regulators, as well as abortion providers and patients. “The fundamental question is: Who can regulate mifepristone?” said Laurie Sobel, associate director of women’s health policy at KFF. “Can states act beyond the FDA? Is the FDA the floor or the ceiling?” While states have clear legal authority to regulate abortion,…

Daiichi Sankyo expects full-year profit to decline significantly in fiscal 2025 due to a 95 billion yen ($610 million) hit, primarily related to its prophylactic antibody-drug conjugate (ADC) manufacturing strategy. The Japanese pharmaceutical company said on Friday that although sales exceeded previous forecasts and are on track to reach new highs, two major costs due to changes in ADC supply plans are expected to result in an extraordinary loss of 149.4 billion yen ($950 million) in the company’s 2025 non-consolidated financial results (PDF). Daiichi recently postponed its annual report to unravel the specific impact of changes in supply, a move…

Infectious H5N1 viruses detected in the air and wastewater of dairy farms, along with evidence of covert infection of cattle, suggest that the outbreak may be spreading in more ways than previously recognized. Research: Surveillance of California dairy farms reveals multiple possible sources of H5N1 influenza virus infection. Image credit: Parilov/Shutterstock.com In a recent study published in PLOS Biologyresearchers conducted a comprehensive surveillance study of California dairy farms to assess the current status of highly pathogenic avian influenza (HPAI) H5N1 in California. The study tested multiple transmission routes (air, wastewater, etc.)., and cow breath) at 14 H5N1-positive dairy farms, revealing…

Recent research published in Journal of Sex Research provide evidence that how couples divide household chores is associated with women’s sexual desire, but this association is highly dependent on personal beliefs about gender roles. The findings suggest that women who prefer equal partnerships tend to have lower sexual desire when they take on more household chores, while women who embrace traditional gender roles do not. These insights highlight how societal expectations about gender shape the dynamics of intimate relationships. Decreased sexual desire is frequently reported among women in long-term relationships with men. Historically, scientists often treated this as an individual…