Author: healthadmin

Gilead Sciences and the World Health Organization (WHO) will strengthen their agreement to eliminate the deadly parasitic disease visceral leishmaniasis (VL) through expanded cooperation focused on delivering treatments to East African countries over the next five years. Under the agreement, Gilead will donate more than 400,000 bottles of AmBisome liposome injection and provide additional financial support of $9.2 million through 2030, the company said in a press release Thursday. Donations will be made mainly to countries that account for approximately 74% of the world’s VL burden, including Bangladesh, Ethiopia, India, Kenya, and Nepal. “Thanks to continued efforts and investment, eradication…

Electronic medical records (EMR) company Canvas Medical on Thursday announced Canvas Studio, a no-code interface that allows clinicians and other medical professionals to build custom EMR workflows. Canvas Medical CEO Adam Farren told Fierce Healthcare that the company is “serving a market” for software developers to customize workflows for end users within ONC-certified EHR platforms. “What Studio does is replace the developer with an AI agent, which allows the end user, whether it’s a clinician or administrative staff user, to use the agent to customize and extend Canvas directly on their own,” Farren said. According to the company, Canvas Studio’s…

Phase 3 results “exceeded” BioMarin’s expectations, according to head of research and development Greg Freeberg, MD, and the California biotech appears poised to win label expansion for its best-selling product, dwarfism treatment Voxzogo. The Canopy-HCH-3 study in children with achondroplasia (HCH) met its primary endpoint, with Voxzogo producing “highly statistically significant” improvements in annual growth velocity (AGV), the company said. In a study of 80 patients between the ages of 3 and 17, the AGV of patients who took Voxzogo was 2.33 centimeters higher than those who took a placebo at week 52. In addition, Voxzogo produced statistically significant increases…

Diseases such as cancer and neurodegenerative diseases often begin with genetic mistakes. But even after scientists identify the genes involved, it remains extremely difficult to turn that knowledge into effective treatments. Many of these diseases are associated with hundreds of mutations spread across different biological pathways, making it difficult to understand how they collectively cause the disease. New research published in nature Here are some potential solutions. Researchers have created a platform called PerturbFate that can systematically track how disease-related genetic changes change cells and identify where those changes ultimately converge. By observing gene regulation in single cells over time,…

More than 21% of adults in the United States experience depression, which significantly impacts their quality of life. Dr. Jyoti Mishra, associate professor of psychiatry at the University of California, San Diego School of Medicine, says many people with mild to moderate depression can improve their symptoms by making adjustments to their daily habits, including sleep, exercise, diet and social interactions. However, depression varies greatly from person to person, so a one-size-fits-all lifestyle approach is not very effective. In a first-of-its-kind study, Mishra and her team developed a machine learning-powered lifestyle coaching program based on data about participants’ moods and…

Depression appears to cause changes in the way the body processes a particular amino acid called valine, rather than the other way around. This discovery is psychopharmacologyhelps explain why metabolic problems are often accompanied by poor mental health. The World Health Organization currently ranks depression as the third leading cause of illness worldwide. Experts predict that it will reach the number one spot by the end of this decade. Major depressive disorder is one of the most common mental health conditions around the world, affecting the way people feel, think, and process daily life. Although depression is primarily known for…

A new study provides clues as to why exercise can improve neurological symptoms in multiple sclerosis (MS) patients. The study, led by researchers at Massachusetts General Brigham and the University Medical Center Hamburg-Eppendorf (UKE), examined levels of the exercise hormone irisin in a mouse model of multiple sclerosis. Researchers found that irisin reduced both clinical symptoms and neuronal loss in experimental models. Furthermore, removal of irisin abolished the protective effect of exercise. Taken together, the researchers’ findings suggest that irisin can protect neurons from inflammation-induced neurodegeneration, making it a potential target for future MS treatments. Results are posted below natural…

For decades, shrinking photonic devices has been much more difficult than miniaturizing electronic components. The challenge comes down to physics. Light cannot be easily confined to very small spaces because the uncertainty principle relates the confinement of light to its wavelength. In visible and near-infrared light, the wavelengths can be up to 1,000 times larger than the de Broglie wavelengths used in electronic circuits. As a result, photonic chips remain relatively large and optical imaging systems face severe resolution limitations. Scientists had previously investigated plasmonics as a possible workaround. This approach uses metal to force light into a space smaller…

HonorHealth Research Institute aims to be the first research facility in the country to launch a new clinical trial aimed at using steam energy to improve the lining of the gastrointestinal tract to control type 2 diabetes without drugs. Type II diabetes is a metabolic disorder that occurs when the body becomes resistant to insulin or when the pancreas cannot produce enough insulin. As a result, blood sugar levels rise, which can lead to serious health complications if not properly managed. The planned minimally invasive endoscopic surgery, called the Restore-1 clinical trial, involves using steam to refresh the mucous membrane,…

Bone is continuously regenerated through a process known as bone remodeling, in which osteoblasts (bone-forming cells) build new bone and osteoclasts (bone-resorbing cells) remove old mineralized tissue. Maintaining a balance between these two cell types is essential for skeletal strength and fracture prevention. When this balance is disrupted, osteoporosis and other metabolic bone diseases can occur. Vitamin K has long been associated with bone health, but its precise biological role remains unknown. Therefore, scientists have sought to understand the molecular pathways by which vitamin K regulates skeletal homeostasis. To address this challenge, a research team led by Dr. Matthew Ferron,…