Author: healthadmin
Karyopharm’s Expovio has stalled in the clinic and market after gaining approval for the treatment of multiple myeloma and achieving sales of $120 million in its third year on the market. On Tuesday, the Massachusetts company provided results from a Phase 3 trial that it hopes will help its nuclear transportation modulator regain momentum. But investors didn’t share the company’s enthusiasm, and the stock price plummeted after the company’s initial public offering, which revealed other financial conditions for the company. By testing Expovio (selinexor) in combination with Incyte and Novartis’ blockbuster Jakafi (ruxolitinib) in patients with first-line myelofibrosis (MF), the…
Despite recent policy uncertainties, Wuxi Biologics’ focus on its US operations will continue to pay off in 2025, with the US accounting for the majority of the record number of projects the CRDMO secured last year. Throughout 2025, the China-based contractor won an impressive 209 new integrated projects, compared to 148 added in 2024, bringing the program total to 945, Wuxi Bio said in its full-year earnings report on Tuesday. About half of these new programs come from the US, which the company says reflects “strong momentum in the US biopharmaceutical sector.” The overall portion of the new project included…
Eli Lilly is scaling back the rollout of its traditional insulin in Europe, with plans to discontinue some products for “commercial reasons.” The company will remove several insulin products in some European countries, including rapid-acting, fast-acting, mixed-acting and long-acting repeat products of its products, including human insulin, insulin lispro and insulin glargine, the European Medicines Agency (EMA) announced on Monday. All of these retirements are expected to occur by the second quarter of 2027, although the specific products and retirement schedules will vary by European country. The exit includes versions of Humalog and Avasagra and comes as Lilly increasingly relies…
You’re reading the web version of DC Diagnosis, STAT’s twice-weekly newsletter about health and medical politics and policy. Sign up here to get it in your inbox on Tuesdays and Thursdays. Far-right influencer and conspiracy theorist Laura Loomer, who stalked Vinay Prasad before he first quit the FDA, is now directing her anger at a crying baby on a plane. News tips and pictures of crying babies (email protected) Or Signal’s John_Wilkerson.07. Who will be the next CDC candidate? The big news this week will likely be the announcement of the nominee for the next CDC director. STAT+ exclusive story…
UIC researchers have successfully repurposed the FDA-approved cancer drug doxorubicin to treat drug-resistant herpes. Their research is published in the journal Drug Resistance Updates. “This opens up an unexpected and potentially rapid path toward treating drug-resistant herpes infections,” said study leader Deepak Shukla, a virologist at the School of Medicine. “HSV-1 infection has serious and sometimes life-threatening consequences, and this drug has the potential to save lives.” Immune-compromised patients, including cancer patients, are particularly vulnerable to HSV-1 infection, which can lead to brain inflammation and organ failure if left untreated. Drug-resistant strains are especially difficult to eradicate. In 2024, Shukla’s…
Insilico Medicine (3696.HK), a clinical-stage drug discovery and development company powered by generative artificial intelligence (AI), today announced a strategic research partnership with ASKA Pharmaceutical Co., Ltd. (“ASKA”), a specialty pharmaceutical company focused on internal medicine, obstetrics and gynecology, and gynecology. The partnership aims to leverage Insilico’s proprietary AI-driven target identification engine, PandaOmics, to identify novel therapeutic targets with high potential for drug development for challenging gynecological diseases such as endometriosis, uterine fibroids, and adenomyosis. Gynecological diseases have long been challenged by difficult diagnoses, limited treatment options, and a significant disease burden, affecting millions of patients worldwide. The World Health…
Atomically thin semiconductors such as tungsten disulfide (WS2) are emerging as key materials for next-generation photonics technologies. Although they are just a single layer of atoms, they can host tightly bound excitons, electron-hole pairs that interact strongly with light. These materials can also generate new colors of light through nonlinear optical effects such as second harmonic generation. These properties hold promise for applications in quantum optics, sensing, and compact on-chip light sources. However, its extreme thinness also creates challenges. With so little material available, optical interactions are limited, and unless the surrounding photonic environment is carefully designed, emission is often…
Recent research published in experimental brain research This provides evidence that elite Rubik’s Cube solvers mentally plan their actions using exactly the same brain patterns as they do physically. This study suggests that highly trained professionals solve the entire puzzle in their heads before even touching it. These findings help explain how the human brain adapts to handle complex tasks that require focused thinking and quick physical movements at the same time. Humans generally have difficulty performing difficult mental arithmetic while performing precise physical movements. For example, people who are texting on their smartphones tend to walk much slower. This…
The Trump administration on Friday announced a legal framework for a single national policy on artificial intelligence. The goal is to create security and safety guardrails for the use of AI, while also preventing states from enacting their own laws. This legal framework is intended to be a blueprint for Congress to guide AI regulation. The framework is based on an executive order signed by President Donald Trump in December aimed at challenging state laws regarding AI. The order does not include any healthcare-specific provisions, but rather aims to limit states’ ability to enact and enforce AI laws, many of…
People who reported spending six or more hours on screens outside of school or work had worse blood pressure, cholesterol, and body mass index (BMI) than those with more limited screen time, according to research presented at the American College of Cardiology’s Annual Scientific Sessions (ACC.26). Screen time was independently associated with these markers of cardiovascular risk, even after accounting for differences in daily physical activity. Researchers say the findings point to excessive time spent playing video games, watching videos and scrolling through social media as a new risk factor among young people, and suggest that clinicians can assess screen…